Faculty Research 1970 - 1979

Title

Defective erythropoietic responses of aged mice not improved by young marrow.

Document Type

Article

Publication Date

1975

Keywords

Anemia-Aplastic: fg, th, Animal, Bloodletting, Bone-Marrow: cy, tr, Erythropoiesis, Female, Hematopoietic-Stem-Cells: ph, Mice, Mice-Inbred-C57BL, SUPPORT-U-S-GOVT-P-H-S, Transplantation-Homologous

JAX Source

J-Gerontol. 1975 May; 30(3):286-8.

Abstract

Defective responses to severe bleeding in 25-mo.-old C57BL/6J mice were not improved by injections of 8-mo.-old marrow cells. Such injections greatly improved responses of genetically anemic W/W-v mice that have defective erythropoietic stem cells. Apparently the defective responses of old mice were not intrinsic to their erythropoietic stem cells.

Please contact the Joan Staats Library for information regarding this document.

Share

COinS