Faculty Research 1970 - 1979

Title

Genetics of mouse antibodies. I. Linkage of the dextran response locus, VH-DEX, to allotype.

Document Type

Article

Publication Date

1975

Keywords

Antibodies: ge, Binding-Sites-Antibody: ge, Chromosome-Mapping, Crosses-Genetic, Dextrans: im, Immunoglobulin-Allotypes, Immunoglobulin-Variable-Region: ge, Immunoglobulins-Heavy-Chain, Linkage-(Genetics), Mice, Mice-Inbred-AKR, Mice-Inbred-BALB-C, Mice-Inbred-C3H, Mice-Inbred-C57BL, Recombination-Genetic, SUPPORT-U-S-GOVT-P-H-S

JAX Source

Eur-J-Immunol. 1975 Nov; 5(11):775-7.

Abstract

The antibody response of mice to alpha-1,3 linked dextran is shown to be controlled by a heavy chain variable region gene, VH-DEX. The map distance between this gene and the heavy chain allotype locus is estimated to be 0.3 recombination units.

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