Faculty Research 1970 - 1979

Title

Primary tumor immunity in nude mice.

Document Type

Article

Publication Date

1977

Keywords

Animals-Newborn, Antigens-Neoplasm, Cell-Transformation-Neoplastic: re, Immunization, Immunologic-Memory: re, Methylcholanthrene, Mice, Mice-Nude: im, Neoplasm-Transplantation, Neoplasms-Experimental: ci, im, SUPPORT-U-S-GOVT-P-H-S

JAX Source

Int-J-Cancer. 1977 May 15; 19(5):688-91.

Abstract

Tumor implants grew better in radiated or in newborn nu/nu mice than in adult nu/nu controls when, and only when, the tumors were demonstrably immunogenic in normal mice. This result suggests primary immunity. No evidence of immunological memory was found by immunization-challenge type experiments in the nude mice.

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