Faculty Research 1970 - 1979

Title

Autosomal phosphoglycerate kinase linked to mouse major histocompatibility complex.

Document Type

Article

Publication Date

1978

Keywords

Crosses-Genetic, Female, Genes-Structural, H-2-Antigens: ge, Isoenzymes: ge, Linkage-(Genetics), Male, Mice, Mice-Inbred-A, Mice-Inbred-C57BL, Phosphoglycerate-Kinase: ge, SUPPORT-U-S-GOVT-P-H-S, Testis: en

JAX Location

42,463

JAX Source

Mol-Gen-Genet. 1978 Jan 17; 158(3):225-8.

Abstract

The mouse autosomal locus that determines the form of phosphoglycerate kinase found only in testes is shown here to be closely linked to but not included within the major histocompatibility complex on chromosome 17. Data are presented that strongly favor the location of this locus, designated Pgk-2, distal to H-2, Qa-1, and Qa-2, and closely associated with T1a. The Pgk-2 strain distribution pattern for 103 inbred and congenic strains of mice is given. Because Pgk-2 is polymorphic among inbred strains, it should be of value in linkage studies.

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