Faculty Research 1970 - 1979

Title

Esterase 13, a new mouse esterase locus with recessive expression and its genetic location on chromosome 9.

Document Type

Article

Publication Date

1978

Keywords

Chromosome-Mapping, Chromosomes, Electrophoresis-Starch-Gel, Esterases: ge, Female, Genes-Recessive, Kidney: en, Male, Mice, Mice-Inbred-Strains: ge, SUPPORT-U-S-GOVT-NON-P-H-S, SUPPORT-U-S-GOVT-P-H-S

JAX Source

Biochem-Genet. 1978 Dec; 16(11-12):1107-12.

Abstract

A new esterase locus (Es-13) has been identified in Musculus. Strains AEJ/GnRk, LG/J, SJL/J, and SWR/J carry a recessive allele, Es-13b, for a locus possibly involved in the posttranslational modification of a kidney esterase. All other strains observed carried the dominant Es-13a allele. Es-13 was mapped on Chr 9 by recombinant inbred lines and by conventional backcrossing experiments. Backcross data produced the following gene order and map distances: Lap-1 (31.6 +/- 7.5 cM) Es-13 (2.6 +/- 2.6 cM) Mod-1.

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