Faculty Research 1970 - 1979

Title

Murine ovarian teratomas and parthenotes as cytogenetic tools.

Authors

E M. Eicher

Document Type

Article

Publication Date

1978

Keywords

Chromosomes: ul, Female, Genes, Mice, Mice-Inbred-Strains, Ovarian-Neoplasms: fg, Parthenogenesis, Phenotype, Recombination-Genetic, SUPPORT-U-S-GOVT-P-H-S, Teratoma: fg

JAX Location

42,576

JAX Source

Cytogenet-Cell-Genet. 1978; 20(1-6):232-9.

Abstract

The origin of murine ovarian teratomas and their use to estimate centromere-to-gene distances is discussed. As an example of how such a system can be used, the distance from the centromere of chromosome 7 to the Gpi-1 locus was determined by analyzing the Gpi-1 phenotypes in 47 ovarian teratomas from Gpi-1a/Gpi-1b females. The percent recombination was estimated to be 10.6. It is suggested that ovarian teratomas and parthenotes may be used for half-tetrad analysis.

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