T-cell receptors: is the repertoire inherently MHC-specific?
Genes-MHC-Class-I, Genes-MHC-Class-II, Immune-Tolerance, Major-Histocompatibility-Complex, Mice, Receptors-Antigen-T-Cell: im, T-Lymphocytes: im, Thymus-Gland: im
Curr Biol 1997 May 1;7(5):R299-300
A debate over whether the observed specificity of the naive T-cell receptor repertoire for major histocompatibility complex molecules arises before or after selection within the thymus has apparently been settled in favour of the former by a series of new experiments.
Janeway, C A.; Chervonsky, A V.; and Sant'Angelo, D, " T-cell receptors: is the repertoire inherently MHC-specific?" (1997). Faculty Research 1990 - 1999. 1001.
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