Faculty Research 1990 - 1999
Differential expression of the zinc finger gene Zfp105 during spermatogenesis.
Document Type
Article
Publication Date
1998
Keywords
Animal, Blotting-Northern, Cell-Differentiation: ge, Chromosome-Mapping, Cloning-Molecular, Conserved-Sequence, DNA-Binding-Proteins: ge, DNA-Complementary: an, Gene-Expression-Regulation-Developmental, Genes-Structural, Human, In-Situ-Hybridization, Male, Mice, Molecular-Sequence-Data, Organ-Specificity: ge, Sequence-Alignment, Sequence-Analysis-DNA, Sequence-Homology-Amino-Acid, Spermatogenesis: ge, SUPPORT-U-S-GOVT-P-H-S, Testis: cy, Zinc-Fingers: ge
First Page
758
Last Page
762
JAX Source
Mamm Genome 1998 Sep;9(9):758-62
Grant
CA37225/CA/NCI, HD31376/HD/NICHD, NS35900/NS/NINDS
Abstract
We report the isolation of Zfp105, the mouse homolog of the human ZNF35 zinc finger gene. Zfp105 and ZNF35 are highly conserved at the protein and nucleotide level, and Zfp105 maps to a region of mouse Chromosome (Chr) 9 that is homologous to the human region containing ZNF35. Zpf105 is highly expressed in the testis, especially in pachytene spermatocytes and round spermatids. The possible role of this gene product in maintaining an ordered germ cell differentiation process is discussed.
Recommended Citation
Przyborski SA,
Knowles BB,
Handel MA,
Gurwitch SA,
Ackerman SL.
Differential expression of the zinc finger gene Zfp105 during spermatogenesis. Mamm Genome 1998 Sep;9(9):758-62