Faculty Research 1990 - 1999
Immunological mutants of the mouse.
Document Type
Article
Publication Date
1991
Keywords
Autoimmunity: ge, Disease-Models-Animal, Immunity: ge, Mice, Mice-Mutant-Strains: im, Mice-SCID: im, SUPPORT-U-S-GOVT-P-H-S
First Page
303
Last Page
311
JAX Source
Am J Anat 1991 Jul; 191(3):303-11.
Grant
CA20408, A130389
Abstract
Mutations at more than 30 loci in mice have been shown to cause deleterious effects on the immune system. Immunologic defects caused by certain of these mutations are determined at the level of hematopoietic progenitor cells or at the level of hematopoietic cell-stromal cell interactions. The immunological mutants described in this paper serve as experimental tools with which to increase our understanding of the development and regulation of the mammalian immune system.
Recommended Citation
Shultz LD.
Immunological mutants of the mouse. Am J Anat 1991 Jul; 191(3):303-11.