Faculty Research 1990 - 1999

Title

Genetic localization of Hao-1, blind-sterile (bs), and Emv-13 on mouse chromosome 2.

Document Type

Article

Publication Date

1992

Keywords

Animal, Blindness: ge, Chromosome-Mapping, Crosses-Genetic, Infertility-Male: ge, Male, Mice: ge, Mouse-Leukemia-Viruses: ge, Mutation, SUPPORT-U-S-GOVT-P-H-S

JAX Source

Genomics 1992 Feb;12(2):403-4

Grant

N01-CO-74101, P40RR01183

Abstract

The blind-sterile (bs) mutation in the mouse was localized on Chromosome 2 between Hao-1 and Emv-13. N2 progeny from a backcross between congenic female 129.AKR-bs Emv-13 mice and (129.AKR-bs/bs x Mus musculus molossinus) F1 male mice were typed by analysis of isozyme variants for Hao-1, visible inspection for bs, and restriction fragment length polymorphism for Emv-13 and Emv-15. Comparison between markers on mouse Chromosome 2 and corresponding markers on human chromosomes suggest that the human homolog of bs will be located on 20q11-q13.

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