Confirmation of the influence of a chromosome 7 locus on susceptibility to audiogenic seizures.
Alleles, Animal, Chromosome-Mapping, Chromosomes, Crosses-Genetic, Disease-Susceptibility: ge, Female, Male, Mice, Mice-Inbred-A, Mice-Inbred-DBA, Seizures: ge, SUPPORT-U-S-GOVT-P-H-S
Mamm Genome 1992;3(5):250-3
Mouse strain differences in susceptibility to audiogenic seizures (AGS) are due to allelic differences at multiple genetic loci. Three loci that influence susceptibility to AGS have been mapped on Chromosomes (Chr) 12, 4, and 7 (Asp-1, Asp-2, and Asp-3, respectively). Here we report evidence that confirms linkage of Asp-3 to c on Chr 7 and parental effects on AGS susceptibility, but not genomic imprinting of Asp-3.
Neumann, P E. and Collins, R L., " Confirmation of the influence of a chromosome 7 locus on susceptibility to audiogenic seizures." (1992). Faculty Research 1990 - 1999. 256.
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