Faculty Research 1990 - 1999

Title

The mouse mutation ulnaless on chromosome 2.

Document Type

Article

Publication Date

1990

Keywords

Chromosome-Mapping, Crosses-Genetic, Extremities, Female, Heterozygote, Linkage-(Genetics), Male, Mice, Mice-Inbred-Strains, Mutation, Phenotype, Reproduction, Support-Non-U, S, -Gov't, Support-U, S, -Gov't-Non-P, H, S, Support-U, S, -Gov't-P, H, S

JAX Location

1,952.

JAX Source

J Hered 1990 Mar-Apr;81(2):151-3.

Grant

RR01183, CA34196

Abstract

The dominant skeletal mutation ulnaless (Ul) in the mouse causes extreme reduction of the radius and ulna and deformities of the tibia and fibula. Penetrance appears to be complete, but the homozygote is not known, as heterozygous males do not breed. We report the linkage of the Ul gene on Chromosome 2, 18 cM proximal to pallid (pa), and describe its phenotypic effects.

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