Faculty Research 1990 - 1999

Title

Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 7 to X.

Document Type

Article

Publication Date

1996

Keywords

Chromosome-Mapping, Crosses-Genetic, Crossing-Over-(Genetics), DNA-Primers, Female, Genetic-Markers, Hereditary-Diseases: ge, Linkage-(Genetics), Male, Mice, Mice-Inbred-Strains: ge, Ovarian-Neoplasms: ge, Polymorphism-(Genetics), Species-Specificity, SUPPORT-U-S-GOVT-P-H-S, X-Chromosome

JAX Source

Mamm Genome 1996 Jul;7(7):526-32

Abstract

The SWXJ recombinant inbred (RI) set was developed for genetic analysis of heritable ovarian tumors. In this report we present data for 223 simple sequence length polymorphisms spanning Chromosomes (Chrs) 7-X to complete the genetic marking of this RI set. The strain distribution patterns (SDP) for these loci were combined with data from 19 other polymorphic genes, resulting in densely marked maps for Chrs 7-X. Combined with the 165 loci for Chr 1-6 reported previously (Svenson et al., Mamm. Genome 6, 867, 1995), the SWXJ RI set represents a powerful tool for mapping genes in neoplastic as well as other heritable disorders.

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