Spx1, a novel X-linked homeobox gene expressed during spermatogenesis.
Animal, Base-Sequence, Gene-Expression-Regulation-Developmental, Genes-Homeobox, Homeodomain-Proteins: ge, Linkage-(Genetics), Male, Mice, Molecular-Sequence-Data, Spermatogenesis: ge, SUPPORT-U-S-GOVT-P-H-S, X-Chromosome
Mech Dev 1997 Jul;65(1-2):87-98
ES07051/ES/NIEHS, HD29599/HD/NICHD, HD32061/HD/NICHD
Spx1, a novel mouse homeobox gene, encodes a homeodomain characteristic of the paired-like class of homeobox genes and has been mapped to the distal end of the X chromosome. Northern blot hybridization of adult tissues detected high levels of a single Spx1 transcript in the testis. Further analysis by in situ hybridization revealed predominant Spx1 expression within the spermatogonia/preleptotene spermatocytes and round spermatids of spermatogenic stages IV-VII. These expression data suggest SPX1 may play a role in the regulation of spermatogenesis.
Branford, W W.; Zhao, G Q.; Valerius, M T.; Weinstein, M; Birkenmeier, E H.; Rowe, L B.; and Potter, S S., " Spx1, a novel X-linked homeobox gene expressed during spermatogenesis." (1997). Faculty Research 1990 - 1999. 874.