Archiving mouse strains by cryopreservation.

C P. Landel

Document Type

Article

Publication Date

2005

First Page

50

Last Page

57

JAX Source

Lab Anim (NY) 2005 Apr; 34(4):50-7.

Abstract

A great deal of time and energy goes into the creation of each new line of transgenic mice; established lines are expensive and labor-intensive to maintain. Archiving of mice by cryopreservation of germ cells or embryos represents a means to free up facility space, while protecting the line from loss due to environmental disasters, genetic drift, or infectious disease. The author reviews the available cryopreservation techniques and presents considerations for setting up a cryopreservation facility.

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