From vivarium to bedside: lessons learned from animal models.
Document Type
Article
Publication Date
2006
Keywords
Disease-Models-Animal, Eye-Diseases-Hereditary, Housing-Animal, Humans, Point-of-Care-Systems, Retinal-Diseases
First Page
123
Last Page
137
JAX Location
see Reprint Collection
JAX Source
Ophthalmic Genet 2006 Dec; 27(4):123-37.
Abstract
In this review, we focus primarily on information obtained by studying mouse models of heritable ocular diseases. These models have proven to be important in advancing our understanding of disease etiology and of pathological consequences of heritable disorders. Careful phenotypic analyses of these models have lead to hypotheses regarding the function of various molecules as well as the mechanisms underlying the observed pathologies. Specific examples of the utility of mouse models in vision research are discussed.
Recommended Citation
Budzynski E,
Lee Y,
Sakamoto K,
Naggert JK,
Nishina PM.
From vivarium to bedside: lessons learned from animal models. Ophthalmic Genet 2006 Dec; 27(4):123-37.