The Mouse Genome Database genotypes::phenotypes.
Document Type
Article
Publication Date
2009
Keywords
Animals, Databases-Genetic, Genes, Genome, Genomics, Genotype, Internet, Mice, Phenotype, Software
JAX Source
Nucleic Acids Res 2009 Jan; 37(Database issue):D712-9.
Abstract
The Mouse Genome Database (MGD, http://www.informatics.jax.org/), integrates genetic, genomic and phenotypic information about the laboratory mouse, a primary animal model for studying human biology and disease. Information in MGD is obtained from diverse sources, including the scientific literature and external databases, such as EntrezGene, UniProt and GenBank. In addition to its extensive collection of phenotypic allele information for mouse genes that is curated from the published biomedical literature and researcher submission, MGI includes a comprehensive representation of mouse genes including sequence, functional (GO) and comparative information. MGD provides a data mining platform that enables the development of translational research hypotheses based on comparative genotype, phenotype and functional analyses. MGI can be accessed by a variety of methods including web-based search forms, a genome sequence browser and downloadable database reports. Programmatic access is available using web services. Recent improvements in MGD described here include the unified mouse gene catalog for NCBI Build 37 of the reference genome assembly, and improved representation of mouse mutants and phenotypes.
Recommended Citation
Blake JA,
Bult CJ,
Eppig JT,
Kadin JA,
Richardson JE.
The Mouse Genome Database genotypes::phenotypes. Nucleic Acids Res 2009 Jan; 37(Database issue):D712-9.