Title

Searching the Mouse Genome Informatics (MGI) resources for information on mouse biology from genotype to phenotype.

Authors

D R. Shaw

Document Type

Article

Publication Date

2009

Keywords

Computational-Biology, Databases-Genetic, Genome, Genomics, Genotype, Information-Storage-and-Retrieval, Mice, Phenotype, User-Computer-Interface

JAX Location

see Reprint Collection (a pdf is available)

JAX Source

Curr Protoc Bioinformatics 2009 Mar; Chapter 1:Unit1.7.

Abstract

The Mouse Genome Informatics (MGI) resource provides the research community with access to information on the genetics, genomics, and biology of the laboratory mouse. Core data in MGI include gene characterization and function, phenotype and disease model descriptions, DNA and protein sequence data, gene expression data, mammalian orthologies, SNPs and PCR polymorphisms, mapping data, and links to other bioinformatics databases. Data integration is supported through the use of standardized nomenclature, and through the use of controlled vocabularies such as the mouse Anatomical Dictionary, the Mammalian Phenotype Ontology, and the Gene Ontologies. MGI extracts and organizes data from primary literature. MGI data are shared with and widely displayed from other bioinformatics resources. The database is updated nightly with curated annotations, and regularly adds new datasets. This unit provides a guide to using the MGI bioinformatics resource.

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