International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: analyzing target autoantigens of humoral immunity in nonobese diabetic mice.
Document Type
Article
Publication Date
2002
Keywords
Autoantibodies, Autoantigens, Diabetes-Mellitus-Insulin-Dependent, Disease-Models-Animal, Glutamate-Decarboxylase, Human, Insulin, Mice, Mice-Inbred-NOD
First Page
1
Last Page
2
JAX Location
see Reprint Collection
JAX Source
Ann N Y Acad Sci 2002 Apr; 958:1-2.
Abstract
The aim of this workshop was to identify autoantibody assays that could provide useful markers of autoimmunity in the NOD mouse model for type 1 diabetes. It was demonstrated that insulin autoantibodies measured by sensitive radiobinding assay are a marker of autoimmunity in NOD mice and draw into question the true nature of GADA and IA-2A in this animal model.
Recommended Citation
Bonifacio E,
Atkinson M,
Eisenbarth G,
Serreze D,
Kay TW,
Lee CE,
Singh B.
International Workshop on Lessons from Animal Models for Human Type 1 Diabetes: analyzing target autoantigens of humoral immunity in nonobese diabetic mice. Ann N Y Acad Sci 2002 Apr; 958:1-2.