Title

Statistical tests for differential expression in cDNA microarray experiments.

Document Type

Article

Publication Date

2003

Keywords

Gene-Expression-Profiling, Matched-Pair-Analysis, Oligonucleotide-Array-Sequence-Analysis, Statistics

JAX Location

see 2003 Staff CD - Library Office

JAX Source

Genome Biol 2003; 4(4):210.

Abstract

Extracting biological information from microarray data requires appropriate statistical methods. The simplest statistical method for detecting differential expression is the t test, which can be used to compare two conditions when there is replication of samples. With more than two conditions, analysis of variance (ANOVA) can be used, and the mixed ANOVA model is a general and powerful approach for microarray experiments with multiple factors and/or several sources of variation.

Please contact the Joan Staats Library for information regarding this document.

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