Genome function and nuclear architecture: from gene expression to nanoscience.
Document Type
Article
Publication Date
2003
Keywords
Cell-Nucleus, Computational-Biology, Gene-Expression-Regulation, Genome, Human, Nanotechnology
First Page
1029
Last Page
1041
JAX Source
Genome Res 2003 Jun; 13(6A):1029-41.
Abstract
Biophysical, chemical, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold considerable promise. A selection of fundamental problems in genome organization and function are reviewed and discussed in the context of these new perspectives and approaches. Advancing these concepts will require coordinated networks of physicists, chemists, and materials scientists collaborating with cell, developmental, and genome biologists.
Recommended Citation
O'Brien TP,
Bult CJ,
Cremer C,
Grunze M,
Knowles BB,
Langowski J,
McNally J,
Pederson T,
Politz JC,
Pombo A,
Schmahl G,
Spatz JP,
van DR.
Genome function and nuclear architecture: from gene expression to nanoscience. Genome Res 2003 Jun; 13(6A):1029-41.