Title

The nature and identification of quantitative trait loci: a community's view.

Document Type

Article

Publication Date

2003

Keywords

Animals-Genetically-Modified, Chromosome-Mapping, Human, Quantitative-Trait-Loci

JAX Source

Nat Rev Genet 2003 Nov; 4(11):911-6

Abstract

This white paper by eighty members of the Complex Trait Consortium presents a community's view on the approaches and statistical analyses that are needed for the identification of genetic loci that determine quantitative traits. Quantitative trait loci (QTLs) can be identified in several ways, but is there a definitive test of whether a candidate locus actually corresponds to a specific QTL?