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Submissions from 2008

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The Mouse Tumor Biology database., D M. Krupke, D A. Begley, J P. Sundberg, C J. Bult, and J T. Eppig

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Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon., M H. Kucherlapati, K Yang, K Fan, M Kuraguchi, D Sonkin, A Rosulek, M Lipkin, R T. Bronson, B J. Aronow, and R Kucherlapati

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Genetic variation in Glp1r expression influences the rate of gastric emptying in mice., K G. Kumar, L O. Byerley, J Volaufova, D J. Drucker, G A. Churchill, R Li, B York, A Zuberi, and B K. Richards

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T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice., P Kumar, H S. Ban, S S. Kim, H Wu, T Pearson, D L. Greiner, K Y. Lee, M Peipp, G H. Fey, N Manjunath, L D. Shultz, S K. Lee, and al et

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Cardiovascular Research and the Laboratory Mouse, Ray Lambert

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Developmental control of sumoylation pathway proteins in mouse male germ cells., Salle S. La, F Sun, X D. Zhang, M J. Matunis, and M A. Handel

Temporal migration of gonadotrophin-releasing hormone-1 neurones is modified in GAD67 knockout mice., J M. Lee, J Tiong, D M. Maddox, B G. Condie, and S Wray

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In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties., C le Viseur, M Hotfilder, S Bomken, K Wilson, S Rottgers, A Schrauder, A Rosemann, J Irving, R W. Stam, L D. Shultz, J Harbott, H Jurgens, M Schrappe, R Pieters, and J Vormoor

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Dense nuclear cataract caused by the gammaB-crystallin S11R point mutation., L Li, B Chang, C Cheng, D Chang, N L. Hawes, C H. Xia, and X Gong

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Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels., R Li, K L. Svenson, L R. Donahue, L L. Peters, and G A. Churchill

Modeling human Philadelphia chromosome-positive leukemia in mice., S Li

Src-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia., S Li

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Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model., M A. Lopez, P S. Pardo, G A. Cox, and A M. Boriek

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Access to immunology through the Gene Ontology., R C. Lovering, E B. Camon, J A. Blake, and A D. Diehl

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Notch signaling regulates bile duct morphogenesis in mice., J Lozier, B McCright, and T Gridley

Mechanisms of DNA double-strand break repair in hematopoietic homeostasis and oncogenesis., S A. Maas, L B. Caddle, and KD Mills

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Analysis of the QTL for sleep homeostasis in mice: Homer1a is a likely candidate., M Mackiewicz, B Paigen, N Naidoo, and A I. Pack

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Whole-body vibration slows the acquisition of fat in mature female rats., G F. Maddalozzo, U T. Iwaniec, R T. Turner, C J. Rosen, and J J. Widrick

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Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses., D M. Maddox, K A. Vessey, G L. Yarbrough, B M. Invergo, D R. Cantrell, S Inayat, V Balannik, W L. Hicks, N L. Hawes, S Byers, R S. Smith, R Hurd, D Howell, R G. Gregg, B Chang, J K. Naggert, J B. Troy, L H. Pinto, P M. Nishina, and M A. McCall

Full-field electroretinography and marked variability in clinical phenotype of Alstrom syndrome., E Malm, V Ponjavic, P M. Nishina, J K. Naggert, E G. Hinman, S Andreasson, J D. Marshall, and C Moller

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The mitochondrial protease AFG3L2 is essential for axonal development., F Maltecca, A Aghaie, D G. Schroeder, L Cassina, B A. Taylor, S J. Phillips, M Malaguti, S Previtali, J L. Guenet, A Quattrini, G A. Cox, and G Casari

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Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation., M Q. Man, G D. Barish, M Schmuth, D Crumrine, Y Barak, S Chang, Y Jiang, R M. Evans, P M. Elias, and K R. Feingold

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The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development., P G. Matteson, J Desai, R Korstanje, G Lazar, T E. Borsuk, J Rollins, S Kadambi, J Joseph, T Rahman, J Wink, R Benayed, B Paigen, and J H. Millonig

Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains., D B. Matthews, E J. Chesler, M N. Cook, J Cockroft, V M. Philip, and D Goldowitz

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Genetic ablation of alphav integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma., J H. McCarty, M Barry, D Crowley, R T. Bronson, Hulbert A. Lacy, and R O. Hynes

[Alstrom syndrome: clinical and genetic features, and a diagnostic guide to foresee complications.], J Mendioroz, E Bermejo, J D. Marshall, J K. Naggert, G B. Collin, and Frias M. Martinez

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The mouse hairy ears mutation exhibits an extended growth (anagen) phase in hair follicles and altered Hoxc gene expression in the ears., S E. Mentzer, J P. Sundberg, A Awgulewitsch, H H. Chao, D A. Carpenter, W D. Zhang, E M. Rinchik, and Y You

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Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies., T Miki, T A. Zwingman, M Wakamori, C M. Lutz, S A. Cook, D A. Hosford, K Herrup, C F. Fletcher, Y Mori, W N. Frankel, and V A. Letts

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mTORC1 promotes survival through translational control of Mcl-1., J R. Mills, Y Hippo, F Robert, S M. Chen, A Malina, C J. Lin, U Trojahn, H G. Wendel, A Charest, R T. Bronson, S C. Kogan, R Nadon, D E. Housman, S W. Lowe, and J Pelletier

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Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure., Y A. Minamishima, J Moslehi, N Bardeesy, D Cullen, R T. Bronson, and W G. Kaelin

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Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk., K Mori, F Blanchard, C Charrier, S Battaglia, K Ando, L Duplomb, L D. Shultz, F Redini, and D Heymann

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Overexpression of innate immune response genes in a model of recessive polycystic kidney disease., M Mrug, J Zhou, Y Woo, X Cui, A J. Szalai, J Novak, G A. Churchill, and Woodford L. Guay

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Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice., A Mukhopadhaya, T Hanafusa, I Jarchum, Y G. Chen, Y Iwai, D V. Serreze, R M. Steinman, K V. Tarbell, and T P. DiLorenzo

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Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice., Y Nakano, Guess C. Longo, D E. Bergstrom, W M. Nauseef, S M. Jones, and B Banfi

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Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers., K Naxerova, C J. Bult, A Peaston, K Fancher, B B. Knowles, S Kasif, and I S. Kohane

Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study., Andreas Neubauer, Kati Maharry, Krzysztof Mrózek, Christian Thiede, Guido Marcucci, Peter Paschka, Robert J Mayer, Richard A Larson, Edison Liu, and Clara D Bloomfield

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A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes., S H. Ng, E Parvanov, P M. Petkov, and K Paigen

Anesthetic considerations for in vivo imaging studies., Nicholson A, Klaunberg B

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The chromosome 11 region from strain 129 provides protection from sex reversal in XYPOS mice., G Nikolova, J S. Sinsheimer, E M. Eicher, and E Vilain

Beyond positional cloning of single gene mutations: use of mouse models to examine allelic variance and to identify genetic modifiers., Patsy M. Nishina and Juergen K. Naggert

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging., P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, S K. Park, A Hartlerode, J Stegmuller, A Hafner, P Loerch, S M. Wright, K D. Mills, A Bonni, B A. Yankner, R Scully, T A. Prolla, F W. Alt, and D A. Sinclair

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Conserving, distributing and managing genetically modified mouse lines by sperm cryopreservation., G C. Ostermeier, M V. Wiles, J S. Farley, and R A. Taft

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The recombinational anatomy of a mouse chromosome., K Paigen, J P. Szatkiewicz, K Sawyer, N Leahy, E D. Parvanov, S H. Ng, J H. Graber, K W. Broman, and P M. Petkov

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AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation., J J. Pang, S L. Boye, A Kumar, A Dinculescu, W Deng, J Li, Q Li, A Rani, T C. Foster, B Chang, N L. Hawes, J H. Boatright, and W W. Hauswirth

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A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination., B L. Patton, B Wang, Y S. Tarumi, K L. Seburn, and R W. Burgess

Human adult testis-derived pluripotent stem cells: revealing plasticity from the germline., C J. Payne and R E. Braun

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Creation of "humanized" mice to study human immunity., T Pearson, D L. Greiner, and L D. Shultz

Humanized SCID mouse models for biomedical research., T Pearson, D L. Greiner, and L D. Shultz

Humanized SCID mouse models for biomedical research., T Pearson, D L. Greiner, and L D. Shultz

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A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function., T Pearson, L D. Shultz, J Lief, L Burzenski, B Gott, T Chase, O Foreman, A A. Rossini, R Bottino, M Trucco, and D L. Greiner

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Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment., T Pearson, L D. Shultz, D Miller, M King, J Laning, W Fodor, A Cuthbert, L Burzenski, B Gott, B Lyons, O Foreman, A A. Rossini, and D L. Greiner

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Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis., J L. Peirce, K W. Broman, L Lu, E J. Chesler, G Zhou, D C. Airey, A E. Birmingham, and R W. Williams

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A critical assessment of Mus musculus gene function prediction using integrated genomic evidence., Castillo L. Pena, M Tasan, C Grant, Z Barutcuoglu, D P. Hill, Farley D. Warde, C Grouios, D Ray, J A. Blake, and al et

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Progressive morphological and functional defects in retinas from alpha1 integrin-null mice., Y W. Peng, M Zallocchi, D T. Meehan, D Delimont, B Chang, N Hawes, W Wang, and D Cosgrove

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Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer., S A. Perera, R S. Maser, H Xia, K McNamara, A Protopopov, L Chen, A F. Hezel, C F. Kim, R T. Bronson, D H. Castrillon, L Chin, N Bardeesy, R A. Depinho, and K K. Wong

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Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages., S B. Petkova, R Yuan, S W. Tsaih, W Schott, D C. Roopenian, and B Paigen

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The dual bromodomain and WD repeat-containing mouse protein BRWD1 is required for normal spermiogenesis and the oocyte-embryo transition., D L. Philipps, K Wigglesworth, S A. Hartford, F Sun, S Pattabiraman, K Schimenti, M Handel, J J. Eppig, and J C. Schimenti

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Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy., Hlavata L. Plecita, M Lessard, J Santorova, J Bewersdorf, and P Jezek

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Evidence for Hox-specified positional identities in adult vasculature., N D. Pruett, R P. Visconti, D F. Jacobs, D Scholz, T McQuinn, J P. Sundberg, and A Awgulewitsch

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Dependence of antibody-mediated presentation of antigen on FcRn., S W. Qiao, K Kobayashi, F E. Johansen, L M. Sollid, J T. Andersen, E Milford, D C. Roopenian, W I. Lencer, and R S. Blumberg

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Light optical precision measurements of the active and inactive Prader-Willi syndrome imprinted regions in human cell nuclei., J Rauch, T A. Knoch, I Solovei, K Teller, S Stein, K Buiting, B Horsthemke, J Langowski, T Cremer, M Hausmann, and C Cremer

Utility of antiPax5 in the diagnosis of lymphoproliferative disorders and neoplasia in mice., J E. Rehg and J P. Sundberg

Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation., P Reifsnyder, W Schott, D Pomerleau, M D. Lessard, B W. Soper, and E H. Leiter

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Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells., J Renaud, G Kerjan, I Sumita, Y Zagar, V Georget, D Kim, C Fouquet, K Suda, M Sanbo, F Suto, S L. Ackerman, K J. Mitchell, H Fujisawa, and A Chedotal

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High-precision structural analysis of subnuclear complexes in fixed and live cells via spatially modulated illumination (SMI) microscopy., J Reymann, D Baddeley, M Gunkel, P Lemmer, W Stadter, T Jegou, K Rippe, C Cremer, and U Birk

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Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1., Moreno A. Robert, J Guiu, Herguido C. Ruiz, M E. Lopez, Esteve J. Ingles, L Riera, A Tipping, T Enver, E Dzierzak, T Gridley, L Espinosa, and A Bigas

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Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice., R F. Robledo, S L. Ciciotte, B Gwynn, K E. Sahr, D M. Gilligan, N Mohandas, and L L. Peters

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Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium., S Rodriguez, H M. Sickles, C Deleonardis, A Alcaraz, T Gridley, and D M. Lin

Regulation of Alstrom syndrome gene expression during adipogenesis and its relationship with fat cell insulin sensitivity., S Romano, G Milan, C Veronese, G B. Collin, J D. Marshall, C Centobene, F Favaretto, Pra C. Dal, A Scarda, S Leandri, J K. Naggert, P Maffei, and R Vettor

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Spatial quantitative analysis of fluorescently labeled nuclear structures: problems, methods, pitfalls., O Ronneberger, D Baddeley, F Scheipl, P J. Verveer, H Burkhardt, C Cremer, L Fahrmeir, T Cremer, and B Joffe

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Bone remodeling, energy metabolism, and the molecular clock., C J. Rosen

Sugar and bone: a not-so sweet story., C J. Rosen

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The mouse polyubiquitin gene Ubb is essential for meiotic progression., K Y. Ryu, S A. Sinnar, L G. Reinholdt, S Vaccari, S Hall, M A. Garcia, T S. Zaitseva, D M. Bouley, K Boekelheide, M A. Handel, M Conti, and R R. Kopito

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Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice., Ngatchou P. Sadate, C J. Payne, A T. Dearth, and R E. Braun

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Human BLyS facilitates engraftment of human PBL derived B cells in immunodeficient mice., M R. Schmidt, M C. Appel, L J. Giassi, D L. Greiner, L D. Shultz, and R T. Woodland

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Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice., D V. Serreze, Rossi C. Choisy, A E. Grier, T M. Holl, H D. Chapman, J R. Gahagan, M A. Osborne, W Zhang, B L. King, A Brown, D Roopenian, and M P. Marron

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NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas., D M. Shin, D J. Shaffer, H Wang, D C. Roopenian, and H C. Morse

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Seeing the world through a new set of glasses: emerging technologies for the study of cell nuclei and chromosomes., L Shopland and J Bewersdorf

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Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice., Abelson M. Simpson, G F. Sonnenberg, H Takita, S J. Yokota, T F. Conway, R J. Kelleher, L D. Shultz, M Barcos, and R B. Bankert

Monitoring of anesthesia., Smith JC, Danneman PJ

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Muscle development is disrupted in zebrafish embryos deficient for fibronectin., C J. Snow, M T. Peterson, A Khalil, and C A. Henry

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Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice., R Strong, R A. Miller, C M. Astle, R A. Floyd, K Flurkey, K L. Hensley, M A. Javors, C Leeuwenburgh, J F. Nelson, and E Ongini

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Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification., I M. Stylianou, J P. Affourtit, K R. Shockley, R Y. Wilpan, F A. Abdi, S Bhardwaj, J Rollins, G A. Churchill, and B Paigen

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Differences in DBA/1J and DBA/2J reveal lipid QTL genes., I M. Stylianou, S R. Langley, K Walsh, Y Chen, C Revenu, and B Paigen

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Integrating mouse anatomy and pathology ontologies into a phenotyping database: tools for data capture and training., J P. Sundberg, B A. Sundberg, and P Schofield

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Regulation of the meiotic prophase I to metaphase I transition in mouse spermatocytes., F Sun and M A. Handel

The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results., J Sun, K A. Silva, K J. McElwee, L E. King, and J P. Sundberg

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Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells., Y Q. Su, K Sugiura, K Wigglesworth, M J. O'Brien, J P. Affourtit, S A. Pangas, M M. Matzuk, and J J. Eppig

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Candidate genes for obesity revealed from a C57BL/6J x 129S1/SvImJ intercross., Z Su, R Korstanje, S W. Tsaih, and B Paigen

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Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJ., Z Su, S W. Tsaih, J Szatkiewicz, Y Shen, and B Paigen

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A new mouse mutant for the LDL receptor identified using ENU mutagenesis., K L. Svenson, N Ahituv, R S. Durgin, H Savage, P A. Magnani, O Foreman, B Paigen, and L L. Peters

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An imputed genotype resource for the laboratory mouse., J P. Szatkiewicz, G L. Beane, Y Ding, L Hutchins, Manuel de Pardo, and G A. Churchill

Virtues and limitations of the preimplantation mouse embryo as a model system., R A. Taft

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An en masse phenotype and function prediction system for Mus musculus., M Tasan, W Tian, D P. Hill, F D. Gibbons, J A. Blake, and F P. Roth

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Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project., Chris F Taylor, Dawn Field, Susanna-Assunta Sansone, Jan Aerts, Rolf Apweiler, Michael Ashburner, Catherine A Ball, Pierre-Alain Binz, Molly Bogue, Tim Booth, Alvis Brazma, Ryan R Brinkman, Adam Michael Clark, Eric W Deutsch, Oliver Fiehn, Jennifer Fostel, Peter Ghazal, Frank Gibson, Tanya Gray, Graeme Grimes, John M Hancock, Nigel W Hardy, Henning Hermjakob, Randall K Julian, Matthew Kane, Carsten Kettner, Christopher Kinsinger, Eugene Kolker, Martin Kuiper, Nicolas Le Novère, Jim Leebens-Mack, Suzanna E Lewis, Phillip Lord, Ann-Marie Mallon, Nishanth Marthandan, Hiroshi Masuya, Ruth McNally, Alexander Mehrle, Norman Morrison, Sandra Orchard, John Quackenbush, James M Reecy, Donald G Robertson, Philippe Rocca-Serra, Henry Rodriguez, Heiko Rosenfelder, Javier Santoyo-Lopez, Richard H Scheuermann, Daniel Schober, Barry Smith, Jason Snape, Christian J Stoeckert, Keith Tipton, Peter Sterk, Andreas Untergasser, Jo Vandesompele, and Stefan Wiemann

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The NLR gene family: a standard nomenclature., J P. Ting, R C. Lovering, E S. Alnemri, J Bertin, J M. Boss, A Godzik, J A. Harton, J P. Hugot, N Inohara, A Mackenzie, L J. Maltais, G Nunez, Y Ogura, J C. Reed, and V Steimle

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Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells., P Varadkar, M Kraman, D Despres, G Ma, J Lozier, and B McCright

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Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters., A Ventura, A G. Young, M M. Winslow, L Lintault, A Meissner, S J. Erkeland, J Newman, R T. Bronson, D Crowley, J R. Stone, R Jaenisch, P A. Sharp, and T Jacks

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Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome., S V. Voronov, S G. Frere, S Giovedi, E A. Pollina, C Borel, H Zhang, C Schmidt, E C. Akeson, M R. Wenk, L Cimasoni, O Arancio, M T. Davisson, S E. Antonarakis, K Gardiner, Camilli P. De, and Paolo G. Di

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Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity., B J. Walters, S L. Campbell, P C. Chen, A P. Taylor, D G. Schroeder, L E. Dobrunz, Tsakonas K. Artavanis, H L. Ploegh, J A. Wilson, G A. Cox, and S M. Wilson