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Submissions from 2010

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GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions., L Mao, K Takamiya, G Thomas, D T. Lin, and R L. Huganir

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BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation., T A. Mitsiadis, D Graf, H Luder, T Gridley, and G Bluteau

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Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch., J S. Mohamed, M A. Lopez, G A. Cox, and A M. Boriek

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Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process., G Moriceau, B Ory, C Riganti, P Pilet, M G. Denis, L D. Shultz, J Monkkonen, F Redini, and al et

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High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias., S Morisot, A S. Wayne, Kashtan O. Bohana, I M. Kaplan, P S. Meltzer, S J. Wheelan, P Brown, R J. Jones, L D. Shultz, and al et

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Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton., J D. Moyer, R B. Nowak, N E. Kim, S K. Larkin, L L. Peters, J Hartwig, F A. Kuypers, and V M. Fowler

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Mouse gestation length is genetically determined., S A. Murray, J L. Morgan, C Kane, Y Sharma, C S. Heffner, J Lake, and L R. Donahue

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Functional hierarchy and reversibility within the murine spermatogenic stem cell compartment., T Nakagawa, M Sharma, Y Nabeshima, R E. Braun, and S Yoshida

Response to Drs Foltz and DeLong's letter to the editor., A, Malcolm R. Nicholson

Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice., S V. Novoselov, H Y. Kim, C M. Astle, D E. Harrison, B Friguet, M E. Moustafa, B A. Carlson, D L. Hatfield, and V N. Gladyshev

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Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse., H Odeh, K L. Hunker, I A. Belyantseva, H Azaiez, L H. Gagnon, N Hagiwara, M J. Skynner, M H. Brilliant, K R. Johnson, H Najmabadi, T B. Friedman, and al et

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Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies., P R. Odgren, C H. Pratt, C A. Mackay, Savas A. Mason, M Curtain, L Shopland, T Ichicki, J P. Sundberg, and L R. Donahue

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Mammalian recombination hot spots: properties, control and evolution., K Paigen and P Petkov

Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency., J Pang, S E. Boye, Y Umino, J Alexander, J Li, X Dai, Q Li, B Chang, and al et

Achromatopsia as a potential candidate for gene therapy., J J. Pang, J Alexander, B Lei, W Deng, K Zhang, Q Li, B Chang, and W W. Hauswirth

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Prdm9 controls activation of mammalian recombination hotspots., E D. Parvanov, P M. Petkov, and K Paigen

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Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation., C J. Payne, S J. Gallagher, O Foreman, J H. Dannenberg, R A. Depinho, and R E. Braun

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Interrogating the transcriptome of oocytes and preimplantation embryos., A E. Peaston, J H. Graber, B B. Knowles, and Vries W. de

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Sequence variation at multiple loci influences red cell hemoglobin concentration., L L. Peters, J A. Shavit, A J. Lambert, S W. Tsaih, Q Li, Z Su, M S. Leduc, B Paigen, G A. Churchill, and D Ginsburg

High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains., V M. Philip, S Duvvuru, B Gomero, T A. Ansah, C D. Blaha, G Mittleman, D Goldowitz, E J. Chesler, and al et

Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease., S Pino, M A. Brehm, Barberis L. Covassin, M King, B Gott, T H. Chase, J Wagner, L Burzenski, O Foreman, D L. Greiner, and L D. Shultz

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Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci., Z Prevorsek, G Gorjanc, B Paigen, and S Horvat

NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection., W J. Racki, L Covassin, M Brehm, S Pino, R Ignotz, R Dunn, J Laning, S K. Graves, A A. Rossini, L D. Shultz, and D L. Greiner

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Validation of multiplex microbead immunoassay for simultaneous serodetection of multiple infectious agents in laboratory mouse., R Ravindran, I H. Khan, V V. Krishnan, M Ziman, L V. Kendall, J M. Frasier, R Bates, S M. Griffey, J R. Fahey, and P A. Luciw

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New and emerging therapeutic agents for the treatment of fibromyalgia: an update., J M. Recla

Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in Sharpin-deficient mice., M L. Renninger, R E. Seymour, L O. Whiteley, J P. Sundberg, and H Hogenesch

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Analysis of novel sph (spherocytosis) alleles in mice reveals allele-specific loss of band 3 and adducin in alpha-spectrin-deficient red cells., R F. Robledo, A J. Lambert, C S. Birkenmeier, M V. Cirlan, A F. Cirlan, D R. Campagna, S E. Lux, and L L. Peters

Human FcRn transgenic mice for pharmacokinetic evaluation of therapeutic antibodies., D C. Roopenian, G J. Christianson, and T J. Sproule

Clinical ramifications of the MHC family Fc receptor FcRn., D C. Roopenian and V Z. Sun

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Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells., Y Saito, H Kitamura, A Hijikata, Murasawa M. Tomizawa, S Tanaka, H Ozawa, A Wake, S Taniguchi, L D. Shultz, O Ohara, and al et

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Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML., Y Saito, N Uchida, S Tanaka, N Suzuki, Murasawa M. Tomizawa, A Sone, Y Najima, S Takagi, Y Aoki, A Wake, S Taniguchi, L D. Shultz, and F Ishikawa

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A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes., F Scheuplein, B Rissiek, J P. Driver, Y G. Chen, Nolte F. Koch, and D V. Serreze

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Research funding. Sustaining the data and bioresource commons., P N. Schofield, J Eppig, E Huala, M H. de Angelis, M Harvey, D Davidson, T Weaver, S Brown, D Smedley, K Schughart, V Aidinis, G Tocchini-Valentini, and J M. Hancock

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Phenotype ontologies for mouse and man: bridging the semantic gap., P N. Schofield, G V. Gkoutos, M Gruenberger, J P. Sundberg, and J M. Hancock

Pathbase and the MPATH ontology. Community resources for mouse histopathology., P N. Schofield, M Gruenberger, and J P. Sundberg

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The mouse model of Down syndrome Ts65Dn presents visual deficits as assessed by pattern visual evoked potentials., McKean J. Scott, B Chang, R E. Hurd, S Nusinowitz, C Schmidt, M T. Davisson, and A C. Costa

Bridging mice to men: using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans., D V. Serreze, J Kulik, and T P. Dilorenzo

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The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice., J B. Shin, Guess C. Longo, L H. Gagnon, K J. Spinelli, J M. Pagana, P A. Wilmarth, L L. David, P G. Gillespie, and K R. Johnson

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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice., L D. Shultz, Y Saito, Y Najima, S Tanaka, T Ochi, M Tomizawa, T Doi, A Sone, N Suzuki, H Fujiwara, M Yasukawa, and F Ishikawa

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Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor., M Siatecka, K E. Sahr, S G. Andersen, M Mezei, J J. Bieker, and L L. Peters

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Finding and sharing: new approaches to registries of databases and services for the biomedical sciences., D Smedley, P Schofield, J Eppig, P Flicek, J K. Heriche, A Lyall, M Ringwald, N Rosenthal, and al et

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A single cis element maintains repression of the key developmental regulator Gata2., Jonathan W Snow, Jennifer J. Trowbridge, Tohru Fujiwara, Nikla E Emambokus, Jeffrey A Grass, Stuart H Orkin, and Emery H Bresnick

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The major locus for mouse adenovirus susceptibility maps to genes of the hematopoietic cell surface-expressed LY6 family., K R. Spindler, A R. Welton, E S. Lim, S Duvvuru, I W. Althaus, J E. Imperiale, A I. Daoud, and E J. Chesler

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A mouse model of heritable cerebrovascular disease., T J. Sproule, J G. Sled, J Wentzell, B Wang, R M. Henkelman, D C. Roopenian, and R W. Burgess

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Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes., M C. Stankewich, B Gwynn, T Ardito, L Ji, J Kim, R F. Robledo, S E. Lux, L L. Peters, and J S. Morrow

Peripherin-reactive antibodies in mouse, rabbit, and human blood., A Strom, B Sonier, H D. Chapman, M Mojibian, G S. Wang, C R. Slatculescu, D V. Serreze, and F W. Scott

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Targeted delivery of small interfering RNA to human dendritic cells to suppress dengue virus infection and associated proinflammatory cytokine production., S Subramanya, S S. Kim, S Abraham, J Yao, M Kumar, P Kumar, V Haridas, S K. Lee, L D. Shultz, D Greiner, M N, and P Shankar

Skin diseases in laboratory mice: approaches to drug target identification and efficacy screening., J P. Sundberg, K A. Silva, C McPhee, and L E. King

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Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes., Fengyun Sun, Kristina Palmer, and Mary Ann Handel

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Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes., F Sun, K Palmer, and M A. Handel

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Assessing the prospects of genome-wide association studies performed in inbred mice., W L. Su, S K. Sieberts, R R. Kleinhanz, K Lux, J Millstein, C Molony, and E E. Schadt

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Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling., Y Q. Su, K Sugiura, Q Li, K Wigglesworth, M M. Matzuk, and J J. Eppig

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Untangling HDL quantitative trait loci on mouse chromosome 5 and identifying Scarb1 and Acads as the underlying genes., Z Su, M S. Leduc, R Korstanje, and B Paigen

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Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse., C Tian, X Z. Liu, F Han, H Yu, Guess C. Longo, B Yang, C Lu, D Yan, and Q Y. Zheng

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Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity., Jennifer J. Trowbridge, Borhane Guezguez, Randall T Moon, and Mickie Bhatia

Genetic analysis of albuminuria in aging mice and concordance with loci for human diabetic nephropathy found in a genome-wide association scan., S W. Tsaih, M G. Pezzolesi, R Yuan, J H. Warram, A S. Krolewski, and R Korstanje

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Effects of alcohol on skeletal response to growth hormone in hypophysectomized rats., R T. Turner, C J. Rosen, and U T. Iwaniec

myc maintains embryonic stem cell pluripotency and self-renewal., N V. Varlakhanova, R F. Cotterman, W N. deVries, J Morgan, L R. Donahue, S Murray, B B. Knowles, and P S. Knoepfler

High-resolution spectral domain optical coherence tomography images of alstrom syndrome., E M. Vingolo, S Salvatore, P L. Grenga, P Maffei, G Milan, and J Marshall

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MDA5 and MAVS mediate type I interferon responses to coxsackie B virus., J P. Wang, A Cerny, D R. Asher, Jones E. Kurt, R T. Bronson, and R W. Finberg

The sophisticated mouse: protecting a precious reagent., M V. Wiles and R A. Taft

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Effects of a high-frequency augmented acoustic environment on parvalbumin immunolabeling in the anteroventral cochlear nucleus of DBA/2J and C57BL/6J mice., J F. Willott, J Vandenbosche, and T Shimizu

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Coordinated expression domains in mammalian genomes., Y H. Woo, M Walker, and G A. Churchill

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Mutations in sterol O-acyltransferase 1 (Soat1) result in hair interior defects in AKR/J mice., B Wu, C S. Potter, K A. Silva, Y Liang, L G. Reinholdt, L M. Alley, L B. Rowe, D C. Roopenian, A Awgulewitsch, and J P. Sundberg

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Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse., G Wu, R B. Sher, G A. Cox, and D E. Vance

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Generation of mice with a conditional null allele of the Jagged2 gene., J Xu, L T. Krebs, and T Gridley

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Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis., K Xu, E Nieuwenhuis, B L. Cohen, W Wang, L Coultas, J Rossant, A Nagy, A Gossler, J G. Sled, T Gridley, and al et

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Enhanced antibody half-life improves in vivo activity., J Zalevsky, A K. Chamberlain, H M. Horton, S Karki, I W. Leung, T J. Sproule, G A. Lazar, D C. Roopenian, and J R. Desjarlais

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Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate., B Zhang, A C. Strauss, S Chu, M Li, Y Ho, K D. Shiang, D S. Snyder, C S. Huettner, L Shultz, T Holyoake, and R Bhatia

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Highly sensitive and reversible silicon nanowire biosensor to study nuclear hormone receptor protein and response element DNA interactions., G J. Zhang, M J. Huang, Z H. Luo, G K. Tay, E J. Lim, E T. Liu, and J S. Thomsen

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Granulosa cell ligand NPPC and its receptor NPR2 maintain meiotic arrest in mouse oocytes., M Zhang, Y Q. Su, K Sugiura, G Xia, and J J. Eppig

MeCP2 is required for normal development of GABAergic circuits in the thalamus., Z W. Zhang, J D. Zak, and H Liu

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Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjogren syndrome., L Zhao, C Rosales, K Seburn, D Ron, and S L. Ackerman