Title

Meiotic DSBs and the control of mammalian recombination.

Document Type

Article

Publication Date

12-1-2012

JAX Source

Cell Res 2012; 22:1624-26.

PMID

22801475

Abstract

The laboratories of Galina Petukhova and R Daniel Camerini-Otero have achieved significant technical advances in determining the genome-wide sites of DNA double-strand breaks (DSBs) where the process of genetic exchange between chromatids during meiosis begins. Applying the new approaches to male meiosis in mice, their experimental results considerably increase our insights into the nature and regulation of these processes.