Title

Human dendritic cell subsets in vaccination.

Document Type

Article

Publication Date

6-2013

JAX Source

Curr Opin Immunol 2013 Jun; 25(3):396-402

PMID

23725656

Abstract

Owing to their properties, dendritic cells (DCs) are often called 'nature's adjuvants' and thus have become the natural targets for antigen delivery. DCs provide an essential link between the innate and the adaptive immune responses. DCs are at the center of the immune system owing to their ability to control both tolerance and immunity. DCs are thus key targets for both preventive and therapeutic vaccination. Herein, we will discuss recent progresses in our understanding of DC subsets physiology as it applies to vaccination. Curr Opin Immunol 2013 Jun; 25(3):396-402