InterMOD: integrated data and tools for the unification of model organism research.
Document Type
Article
Publication Date
5-8-2013
Keywords
Animals, Databases, Factual, Databases, Genetic, Genome, Genomics, Models, Genetic
JAX Source
Sci Rep 2013 May 8; 3:1802.
Volume
3
First Page
1802
Last Page
1802
ISSN
2045-2322
PMID
23652793
Abstract
Model organisms are widely used for understanding basic biology, and have significantly contributed to the study of human disease. In recent years, genomic analysis has provided extensive evidence of widespread conservation of gene sequence and function amongst eukaryotes, allowing insights from model organisms to help decipher gene function in a wider range of species. The InterMOD consortium is developing an infrastructure based around the InterMine data warehouse system to integrate genomic and functional data from a number of key model organisms, leading the way to improved cross-species research. So far including budding yeast, nematode worm, fruit fly, zebrafish, rat and mouse, the project has set up data warehouses, synchronized data models, and created analysis tools and links between data from different species. The project unites a number of major model organism databases, improving both the consistency and accessibility of comparative research, to the benefit of the wider scientific community. Sci Rep 2013 May 8; 3:1802.
Recommended Citation
Sullivan J,
Karra K,
Moxon S,
Vallejos A,
Motenko H,
Wong J,
Aleksic J,
Balakrishnan R,
Binkley G,
Harris T,
Hitz B,
Jayaraman P,
Lyne R,
Neuhauser S,
Pich C,
Smith R,
Trinh Q,
Cherry J,
Richardson J,
Stein L,
Twigger S,
Westerfield M,
Worthey E,
Micklem G.
InterMOD: integrated data and tools for the unification of model organism research. Sci Rep 2013 May 8; 3:1802.