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Submissions from 2013

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Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators., Zeynep Madak-Erdogan, Tze-Howe Charn, Yan Jiang, Edison Liu, John A Katzenellenbogen, and Benita S Katzenellenbogen

Extreme clinical variability of dilated cardiomyopathy in two siblings with Alström syndrome., Jamal Mahamid, Avraham Lorber, Yoseph Horovitz, Stavit A Shalev, Gayle B. Collin, Juergen K. Naggert, Jan D. Marshall, and Ronen Spiegel

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Transforming growth factor β-induced peritoneal fibrosis is mouse strain dependent., Peter J Margetts, Catherine Hoff, Limin Liu, Ron Korstanje, Louise Walkin, Angela Summers, Sarah Herrick, and Paul Brenchley

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Clinical utility gene card for: Alström Syndrome - update 2013., Jan D. Marshall, Pietro Maffei, Sebastian Beck, Timothy G Barrett, Richard Paisey, and Juergen K. Naggert

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IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R., Christopher E Martin, Ester M M van Leeuwen, Se Jin Im, Derry C. Roopenian, Young-Chul Sung, and Charles D Surh

A new approach for the study of the chemical composition of bordered pit membranes: 4Pi and confocal laser scanning microscopy., Daniela Maschek, Barry Goodell, Jody Jellison, Mark Lessard, and Holger Militz

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Low-grade and high-grade serous Mullerian carcinoma: Review and analysis of publicly available gene expression profiles., Taymaa May, Melina Shoni, Christopher P Crum, Wa Xian, Vinod Vathipadiekal, Michael Birrer, Barry Rosen, Alicia Tone, and K Joan Murphy

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IBI* series winner. Students as collaborators in systems biology research., Susan McClatchy, Deborah McGann, Robert Gotwals, Amanda Baskett, and Gary Churchill

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What causes alopecia areata?, K J McElwee, A Gilhar, D J Tobin, Y Ramot, John P. Sundberg, M Nakamura, M Bertolini, S Inui, Y Tokura, L E King, B Duque-Estrada, A Tosti, A Keren, S Itami, Y Shoenfeld, A Zlotogorski, R Paus, Bruna Duque-Estrada, Antonella Tosti, Kevin J McElwee, Amos Gilhar, Aviad Keren, Marta Bertolini, Yehuda Shoenfeld, Motonobu Nakamura, Yoshiki Tokura, John P Sundberg, Lloyd E King, Yuval Ramot, Abraham Zlotogorski, Desmond J Tobin, Ralf Paus, Shigeki Inui, and Satoshi Itami

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IL-21 Is a Double-Edged Sword in the Systemic Lupus Erythematosus-like Disease of BXSB.Yaa Mice., Caroline G. McPhee, Jason A. Bubier, Thomas J. Sproule, Giljun Park, Martin P Steinbuck, William H. Schott, Gregory J. Christianson, Herbert C Morse, and Derry C. Roopenian

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Ontology based molecular signatures for immune cell types via gene expression analysis., Terrance F Meehan, Nicole A Vasilevsky, Christopher J Mungall, David S Dougall, Melissa A Haendel, Judith A. Blake, and Alexander D Diehl

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DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements., Tim R Mercer, Stacey L Edwards, Michael B Clark, Shane J Neph, Hao Wang, Andrew B Stergachis, Sam John, Richard Sandstrom, Guoliang Li, Kuljeet S Sandhu, Yijun Ruan, Lars K Nielsen, John S Mattick, and John A Stamatoyannopoulos

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Tumor suppression: Putting p53 in context., Kevin D. Mills

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Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins., Hamid Mirzaei, Theo A Knijnenburg, Bong Kim, Max Robinson, Paola Picotti, Gregory W. Carter, Song Li, David J Dilworth, Jimmy K Eng, John D Aitchison, Ilya Shmulevich, Timothy Galitski, Ruedi Aebersold, and Jeffrey Ranish

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Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction., Junaith S Mohamed, Michael A Lopez, Gregory A. Cox, and Aladin M Boriek

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DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8+ T cells independently of PD-1 and PD-L1., Gayatri Mukherjee, Ari Geliebter, Jeffrey Babad, Pere Santamaria, David V. Serreze, Gordon J Freeman, Kristin V Tarbell, Arlene Sharpe, and Teresa P Dilorenzo

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Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of Mammalian sex determination., Steven C. Munger, Anirudh Natarajan, Loren L Looger, Uwe Ohler, and Blanche Capel

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Meeting report of the 26th International Mammalian Genome Conference., Melissa A Musser, Steven C. Munger, and Teresa M Gunn

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Cholesterol metabolism and Rett syndrome pathogenesis., Gabor Nagy and Susan L. Ackerman

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Notch1 induced brain tumor models the sonic hedgehog subgroup of human medulloblastoma., Sivaraman Natarajan, Yaochen Li, Emily E Miller, David J Shih, Michael D Taylor, Timothy M. Stearns, Roderick T Bronson, Susan L. Ackerman, Jeong Yoon, and Kyuson Yun

Differential expression of p-ERM, a marker of cell polarity, in benign and neoplastic oviductal epithelium., Gang Ning, Jonathan G Bijron, Ju Yuan, Michelle S Hirsch, Frank D. McKeon, Marisa R Nucci, Christopher P Crum, and Wa Xian

Genetic analysis of mesangial matrix expansion in aging mice and identification of far2 as a candidate gene., Gerda A Noordmans, Christina R Caputo, Yuan Huang, Susan M Sheehan, Marian Bulthuis, Peter Heeringa, Jan-Luuk Hillebrands, Harry van Goor, and Ron Korstanje

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Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines., Gerlinde Obermoser, Scott Presnell, Kelly Domico, Hui Xu, Yuanyuan Wang, Esperanza Anguiano, Luann Thompson-Snipes, Rajaram Ranganathan, Brad Zeitner, Anna Bjork, David Anderson, Cate Speake, Emily Ruchaud, Jason Skinner, Laia Alsina, Mamta Sharma, Helene Dutartre, Alma Cepika, Elisabeth Israelsson, Phuong Nguyen, Quynh-Anh Nguyen, A Carson Harrod, Sandra M Zurawski, Virginia Pascual, Hideki Ueno, Gerald T Nepom, Charlie Quinn, Derek Blankenship, Karolina Palucka, Jacques Banchereau, and Damien Chaussabel

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Getting ready for the Human Phenome Project: the 2012 forum of the Human Variome Project., William S Oetting, Peter N Robinson, Marc S Greenblatt, Richard G Cotton, Tim Beck, John C Carey, Sandra C Doelken, Marta Girdea, Tudor Groza, Carol M Hamilton, Ada Hamosh, Berit Kerner, Jacqueline A L MacArthur, Donna R Maglott, Barend Mons, Heidi L Rehm, Paul N Schofield, Beverly A Searle, Damian Smedley, Cynthia Smith, Inge Thomsen Bernstein, Andreas Zankl, and Eric Y Zhao

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Reference Guide to Mouse Models of Spinal Muscular Atrophy, Melissa Osborne and Cathleen Lutz

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SeqFold: Genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data., Zhengqing Ouyang, Michael P Snyder, and Howard Y Chang

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Dendritic-cell-based therapeutic cancer vaccines., Karolina Palucka and Jacques Banchereau

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Human dendritic cell subsets in vaccination., Karolina Palucka and Jacques Banchereau

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Genome-wide association studies of maximum number of drinks., Yue Pan, Xingguang Luo, Xuefeng Liu, Long-Yang Wu, Qunyuan Zhang, Liang Wang, Weize Wang, Lingjun Zuo, and Ke-Sheng Wang

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The Vertebrate Trait Ontology: a controlled vocabulary for the annotation of trait data across species., Carissa A Park, Susan M. Bello, Cynthia Smith, Zhi-Liang Hu, Diane H Munzenmaier, Rajni Nigam, Jennifer R Smith, Mary Shimoyama, Janan T. Eppig, and James M Reecy

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Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants., Stephen C J Parker, Michael L. Stitzel, D Leland Taylor, Jose Miguel Orozco, Michael R Erdos, Jennifer A Akiyama, Kelly Lammerts van Bueren, Peter S Chines, Narisu Narisu, Brian L Black, Axel Visel, Len A Pennacchio, and Francis S Collins

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Elevated id2 expression results in precocious neural stem cell depletion and abnormal brain development., Hee Jung Park, Mingi Hong, Roderick T Bronson, Mark A Israel, Wayne N. Frankel, and Kyuson Yun

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Murine adipose tissue-derived stromal cell apoptosis and susceptibility to oxidative stress in vitro are regulated by genetic background., Robert Pazdro and David E. Harrison

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Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions., Jia Peng, Qinglei Li, Karen Wigglesworth, Adithya Rangarajan, Chandramohan Kattamuri, Randall T Peterson, John J. Eppig, Thomas B Thompson, and Martin M Matzuk

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Reply to Mottershead et al.: GDF9:BMP15 heterodimers are potent regulators of ovarian functions., Jia Peng, Qinglei Li, Karen Wigglesworth, Adithya Rangarajan, Chandramohan Kattamuri, Randall T Peterson, John J. Eppig, Thomas B Thompson, and Martin M Matzuk

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β-Actin and fascin-2 cooperate to maintain stereocilia length., Benjamin J Perrin, Dana M Strandjord, Praveena Narayanan, Davin M Henderson, Kenneth R. Johnson, and James M Ervasti

The scat mouse model highlights RASA3, a GTPase activating protein, as a key regulator of vertebrate erythropoiesis and megakaryopoiesis., Luanne L. Peters, Barry H Paw, and Lionel Blanc

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Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease., Gregory B Potter, Marta Santos, Muriel T. Davisson, David H Rowitch, Dan L Marks, Ernesto R Bongarzone, and Magdalena A Petryniak

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SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes., Jeroen Pouwels, Nicola De Franceschi, Pia Rantakari, Kaisa Auvinen, Marika Karikoski, Elina Mattila, Christopher Potter, John P. Sundberg, Nancy Hogg, Carl G Gahmberg, Marko Salmi, and Johanna Ivaska

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Epicutaneous model of community-acquired Staphylococcus aureus skin infections., Ranjani Prabhakara, Oded Foreman, Roberto De Pascalis, Gloria M Lee, Roger D Plaut, Stanley Y Kim, Scott Stibitz, Karen L Elkins, and Tod J Merkel

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Cholera toxin subunit B-peptide fusion proteins reveal impaired oral tolerance induction in diabetes-prone but not in diabetes-resistant mice., Maximiliano Presa, Angela Zarama Ortiz, Nahir Garabatos, Cristina Izquierdo, Elisa I Rivas, Luc Teyton, Conchi Mora, David V. Serreze, and Thomas Stratmann

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Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain., Victoria A Rafalski, Peggy P Ho, Jamie O Brett, Duygu Ucar, Jason C Dugas, Elizabeth A Pollina, Lionel M L Chow, Adiljan Ibrahim, Suzanne J Baker, Ben A Barres, Lawrence Steinman, and Anne Brunet

The immunologic functions of the neonatal Fc receptor for IgG., Timo Rath, Timothy T Kuo, Kristi Baker, Shuo-Wang Qiao, Kanna Kobayashi, Masaru Yoshida, Derry C. Roopenian, Edda Fiebiger, Wayne I Lencer, and Richard S Blumberg

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Strain-specific variations in cation content and transport in mouse erythrocytes., Alicia Rivera, Robert Y L Zee, Seth L Alper, Luanne L. Peters, and Carlo Brugnara

Copy number variation prevalence in known asthma genes and their impact on asthma susceptibility., A J Rogers, J-H Chu, K Darvishi, I Ionita-Laza, H Lehmann, R Mills, Charles Lee, and B A Raby

Alström syndrome is associated with short stature and reduced GH reserve., S Romano, P Maffei, V Bettini, G Milan, F Favaretto, M Gardiman, Jan D. Marshall, N A Greggio, G B Pozzan, G B Collin, Juergen K. Naggert, R Bronson, and R Vettor

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The Gene Ontology (GO) Cellular Component Ontology: integration with SAO (Subcellular Anatomy Ontology) and other recent developments., Paola Roncaglia, Maryann E Martone, David P. Hill, Tanya Z Berardini, Rebecca E Foulger, Fahim T Imam, Harold J. Drabkin, Christopher J Mungall, and Jane Lomax

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High-throughput quantification of the mechanical competence of murine femora--a highly automated approach for large-scale genetic studies., D Ruffoni, T Kohler, R Voide, A J Wirth, Leah Rae Donahue, R Müller, and G H van Lenthe

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A pyrrolo-pyrimidine derivative targets human primary AML stem cells in vivo., Yoriko Saito, Hitomi Yuki, Mitsuo Kuratani, Yoshinobu Hashizume, Shinsuke Takagi, Teruki Honma, Akiko Tanaka, Mikako Shirouzu, Junko Mikuni, Noriko Handa, Ikuko Ogahara, Akiko Sone, Yuho Najima, Yuri Tomabechi, Motoaki Wakiyama, Naoyuki Uchida, Mariko Tomizawa-Murasawa, Akiko Kaneko, Satoshi Tanaka, Nahoko Suzuki, Hiroshi Kajita, Yuki Aoki, Osamu Ohara, Leonard D. Shultz, Takehiro Fukami, Toshio Goto, Shuichi Taniguchi, Shigeyuki Yokoyama, and Fumihiko Ishikawa

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Myosin 6 is required for iris development and normal function of the outer retina., Ivy S Samuels, Brent A Bell, Gwen Sturgill-Short, Lindsey A Ebke, Mary Rayborn, Lanying Shi, Patsy M. Nishina, and Neal S Peachey

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AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice., Kerry J Schimenti, Sky K Feuer, Laurie B Griffin, Nancy R Graham, Claire A Bovet, Suzanne Hartford, Janice Pendola, Carl Lessard, John C Schimenti, and Jeremy O Ward

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Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice., Erica B Schleifman, Nicole Ali McNeer, Andrew Jackson, Jennifer Yamtich, Michael A Brehm, Leonard D. Shultz, Dale L Greiner, Priti Kumar, W Mark Saltzman, and Peter M Glazer

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IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans., Nathalie Schmitt, Jacinta Bustamante, Laure Bourdery, Salah Eddine Bentebibel, Stephanie Boisson-Dupuis, Fran Hamlin, Mau V Tran, Derek Blankenship, Virginia Pascual, Daniel A Savino, Jacques Banchereau, Jean-Laurent Casanova, and Hideki Ueno

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The importance of the intracortical canal network for murine bone mechanics., Philipp Schneider, Romain Voide, Marco Stampanoni, Leah Rae Donahue, and Ralph Müller

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The mouse pathology ontology, MPATH; structure and applications., Paul N Schofield, John P. Sundberg, Beth A. Sundberg, Colin McKerlie, and Georgios V Gkoutos

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Loss of function of the mouse Sharpin gene results in Peyer's patch regression., Rosemarie Seymour, Bobbi-Jo Shirley, Harm Hogenesch, Leonard D. Shultz, and John P. Sundberg

Surgical Methods for Full-Thickness Skin Grafts to Induce Alopecia Areata in C3H/HeJ Mice., Kathleen A. Silva and John P. Sundberg

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Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus., Kerri N Smith, Sarah J Halfyard, Edward S Yaskowiak, Kathryn L. Shultz, Wesley G. Beamer, and Ann M Dorward

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Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice., Randy Strong, Richard A Miller, Clinton M. Astle, Joseph A Baur, Rafael de Cabo, Elizabeth Fernandez, Wen Guo, Martin Javors, James L Kirkland, James F Nelson, David A Sinclair, Bruce Teter, David Williams, Nurulain Zaveri, Nancy L Nadon, and David E. Harrison

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InterMOD: integrated data and tools for the unification of model organism research., Julie Sullivan, Kalpana Karra, Sierra A T Moxon, Andrew Vallejos, Howie Motenko, J D Wong, Jelena Aleksic, Rama Balakrishnan, Gail Binkley, Todd Harris, Benjamin Hitz, Pushkala Jayaraman, Rachel Lyne, Steven Neuhauser, Christian Pich, Richard N Smith, Quang Trinh, J Michael Cherry, Joel E Richardson, Lincoln Stein, Simon Twigger, Monte Westerfield, Elizabeth Worthey, and Gos Micklem

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Alopecia areata: updates from the mouse perspective., John P. Sundberg, Annerose Berndt, Kathleen A. Silva, Victoria E. Kennedy, Beth A. Sundberg, Helen B Everts, Robert H Rice, and Lloyd E King

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The Cinderella Effect: Searching for the Best Fit between Mouse Models and Human Diseases., John P. Sundberg, Derry C. Roopenian, Edison Liu, and Paul N Schofield

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Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice., Wenzhi Sun, Jacy L Wagnon, Connie L. Mahaffey, Michael Briese, Jernej Ule, and Wayne N. Frankel

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The perfect host: a mouse host embryo facilitating more efficient germ line transmission of genetically modified embryonic stem cells., Robert A. Taft, Benjamin E. Low, Shannon L. Byers, Stephen A. Murray, Peter Kutny, and Michael V. Wiles

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Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury., T Tanaka, Y Fujita, M Ueno, Leonard D. Shultz, and T Yamashita

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Atypical presentation and a novel mutation in ALMS1: implications for clinical and molecular diagnostic strategies for Alström syndrome., S Taşdemir, A Güzel-Ozantürk, Jan D. Marshall, Gayle B. Collin, R K Ozgül, N Narin, M Dündar, and Juergen K. Naggert

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Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy., Alexander S Taylor, Jacqueline J Glascock, Ferrill F Rose, Cathleen Lutz, and Christian L Lorson

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ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63., Luca Tordella, Sofia Koch, Victoria Salter, Anna Pagotto, Jessica B Doondeea, Stephan M Feller, Indrika Ratnayaka, Shan Zhong, Robert D Goldin, Guillermina Lozano, Frank D. McKeon, Mahvash Tavassoli, Florian Fritzsche, Gerhard F Huber, Matthias Rössle, Holger Moch, and Xin Lu

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Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort., Sushil Tripathi, Karen R. Christie, Rama Balakrishnan, Rachael Huntley, David P. Hill, Liv Thommesen, Judith A. Blake, Martin Kuiper, and Astrid Lægreid

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Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer., Philipp Tropberger, Sebastian Pott, Claudia Keller, Kinga Kamieniarz-Gdula, Matthieu Caron, Florian Richter, Guohong Li, Gerhard Mittler, Edison T. Liu, Marc Bühler, Raphael Margueron, and Robert Schneider

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CAPE: An R Package for Combined Analysis of Pleiotropy and Epistasis., Anna L. Tyler, Wei Lu, Justin J Hendrick, Vivek M. Philip, and Gregory W. Carter

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A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination., Bao Q Vuong, Kayleigh Herrick-Reynolds, Bharat Vaidyanathan, Joseph N Pucella, Anna J Ucher, Nina M. Donghia, Xiwen Gu, Laura Nicolas, Urszula Nowak, Numa Rahman, Matthew P Strout, Kevin D. Mills, Janet Stavnezer, and Jayanta Chaudhuri

Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks., Joel P. Wagner, Alejandro Wolf-Yadlin, Mark Sevecka, Jennifer K Grenier, David E Root, Douglas A Lauffenburger, and Gavin MacBeath

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The role of mouse strain differences in the susceptibility to fibrosis: a systematic review., Louise Walkin, Sarah E Herrick, Angela Summers, Paul E Brenchley, Catherine M Hoff, Ron Korstanje, and Peter J Margetts

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Effects of low-level organic selenium on lead-induced alterations in neural cell adhesion molecules., Mao Wang, Hongjun Fu, Yongmei Xiao, Baomin Ai, Qing Wei, Shuyu Wang, Tao Liu, Liuqing Ye, and Qiansheng Hu

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Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing., Yue Wan, Kun Qu, Zhengqing Ouyang, and Howard Y Chang

Pathology of rodent models of intestinal cancer: progress report and recommendations., Mary Kay Washington, Anne E Powell, Ruth Sullivan, John P. Sundberg, Nicholas Wright, Robert J Coffey, and William F Dove

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FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis., Ashley E Webb, Elizabeth A Pollina, Thomas Vierbuchen, Noelia Urbán, Duygu Ucar, Dena S Leeman, Ben Martynoga, Madhavi Sewak, Thomas A Rando, François Guillemot, Marius Wernig, and Anne Brunet

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Introduction to mechanisms of neural circuit formation., Joshua A Weiner, James D Jontes, and Robert W. Burgess

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Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa., Katherine J Wert, Richard J Davis, Javier Sancho-Pelluz, Patsy M. Nishina, and Stephen H Tsang

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Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes., Karen Wigglesworth, Kyung-Bon Lee, Marilyn J. O'Brien, Jia Peng, Martin M Matzuk, and John J. Eppig

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Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma., J L Wiggs, Gareth R. Howell, K Linkroum, W Abdrabou, E Hodges, Catherine E. Braine, L R Pasquale, G J Hannon, J L Haines, and Simon W M John

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Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma., Pete A. Williams, Gareth R. Howell, Jessica M Barbay, Catherine E. Braine, Gregory L Sousa, Simon W M John, and James E Morgan

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Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease., Pete A. Williams, Rebecca A Thirgood, Huw Oliphant, Aura Frizzati, Elinor Littlewood, Marcela Votruba, Mark A Good, Julie Williams, and James E Morgan

Inflammatory dilated cardiomyopathy in Abcg5-deficient mice., Dennis W Wilson, Karen L Oslund, Bonnie L. Lyons, Oded Foreman, Lisa Burzenski, Karen L. Svenson, Thomas H Chase, and Leonard D. Shultz

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R164C mutation in FOXQ1 H3 domain affects formation of the hair medulla., Baojin Wu, C Herbert Pratt, Christopher S. Potter, Kathleen A. Silva, Victoria E. Kennedy, and John P Sundberg

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Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A., Jian Xu, Daniel E Bauer, Marc A Kerenyi, Thuy D Vo, Serena Hou, Yu-Jung Hsu, Huilan Yao, Jennifer J. Trowbridge, Gail Mandel, and Stuart H Orkin

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Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles., Jingxia Xu and Thomas Gridley

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The draft genome of sweet orange (Citrus sinensis)., Qiang Xu, Ling-Ling Chen, Xiaoan Ruan, Dijun Chen, Andan Zhu, Chunli Chen, Denis Bertrand, Wen-Biao Jiao, Bao-Hai Hao, Matthew P Lyon, Jiongjiong Chen, Song Gao, Feng Xing, Hong Lan, Ji-Wei Chang, Xianhong Ge, Yang Lei, Qun Hu, Yin Miao, Lun Wang, Shixin Xiao, Manosh Kumar Biswas, Wenfang Zeng, Fei Guo, Hongbo Cao, Xiaoming Yang, Xi-Wen Xu, Yun-Jiang Cheng, Juan Xu, Ji-Hong Liu, Oscar Junhong Luo, Zhonghui Tang, Wen-Wu Guo, Hanhui Kuang, Hong-Yu Zhang, Mikeal L Roose, Niranjan Nagarajan, Xiu-Xin Deng, and Yijun Ruan

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Diverse mechanisms of somatic structural variations in human cancer genomes., Lixing Yang, Lovelace J Luquette, Nils Gehlenborg, Ruibin Xi, Psalm S Haseley, Chih-Heng Hsieh, Chengsheng Zhang, Xiaojia Ren, Alexei Protopopov, Lynda Chin, Raju Kucherlapati, Charles Lee, and Peter J Park

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Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance., Lan Ye, Anne L Widlund, Carrie A Sims, Dudley W Lamming, Yuxia Guan, James G Davis, David M Sabatini, David E. Harrison, Ole Vang, and Joseph A Baur

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Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model., Sandra J Yokota, John G Facciponte, Raymond J Kelleher, Leonard D. Shultz, Jenni L Loyall, Robert R Parsons, Kunle Odunsi, John G Frelinger, Edith M Lord, Scott A Gerber, Sathy V Balu-Iyer, and Richard B Bankert

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Genetic regulation of life span, metabolism, and body weight in Pohn, a new wild-derived mouse strain., Rong Yuan, Kevin Flurkey, Qingying Meng, Clinton M Astle, and David E. Harrison

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Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-β., Chun I Yu, Christian Becker, Yuanyuan Wang, Florentina Marches, Julie Helft, Marylene Leboeuf, Esperanza Anguiano, Stephane Pourpe, Kristina Goller, Virginia Pascual, Jacques Banchereau, Miriam Merad, and Karolina Palucka

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Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-β-catenin signaling., Bin Zhang, Min Li, Tinisha McDonald, Tessa L Holyoake, Randall T Moon, Dario Campana, Leonard D. Shultz, and Ravi Bhatia

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Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations., Yubo Zhang, Chee-Hong Wong, Ramon Y Birnbaum, Guoliang Li, Rebecca Favaro, Chew Yee Ngan, Joanne Lim, Eunice Tai, Huay Mei Poh, Eleanor Wong, Fabianus Hendriyan Mulawadi, Wing-Kin Sung, Silvia Nicolis, Nadav Ahituv, Yijun Ruan, and Chia-Lin Wei

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Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses., Zhong-Wei Zhang, Matthew Peterson, and Hong Liu