Title

SnapShot: Cancer Vaccines.

Document Type

Article

Publication Date

4-10-2014

JAX Source

Cell 2014 Apr 10; 157(2):516-516e1.

PMID

24725415

Abstract

This SnapShot illustrates the main concepts and underlying biology of therapeutic vaccination in cancer. Dendritic cells (DCs) are an essential component of vaccination through their capacity to capture, process, and present antigens to T cells. We have come a long way in our understanding of what is needed to elicit therapeutic immunity when cancer escapes the natural barrier of protective immunity. This progress enables the development of novel vaccines.

Cell 2014 Apr 10; 157(2):516-516e1.