Title

Applying "gold standards" to in-vitro-derived germ cells.

Document Type

Article

Publication Date

6-5-2014

JAX Source

Cell 2014 Jun 5; 157(6):1257-61.

PMID

24906145

Abstract

Germ cells are the ultimate stem cells, and reports of their in vitro derivation generate excitement due to potential applications in reproductive medicine. To date, there is no firm evidence that meiosis, the hallmark of gametogenesis, can be faithfully replicated outside of the gonad. We propose benchmarks for evaluating in vitro derivation of germ cells, facilitating realization of their potential. Cell 2014 Jun 5; 157(6):1257-61.