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Submissions from 2015

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Applying the ARRIVE Guidelines to an In Vivo Database., Natasha A Karp, Terry F Meehan, Hugh Morgan, Jeremy C Mason, Andrew Blake, Natalja Kurbatova, Damian Smedley, Julius Jacobsen, Richard F Mott, Vivek Iyer, Peter Matthews, David G Melvin, Sara Wells, Ann M Flenniken, Hiroshi Masuya, Shigeharu Wakana, Jacqueline K White, K C Kent Lloyd, Corey L Reynolds, Richard Paylor, David B West, Karen L. Svenson, Elissa J. Chesler, Martin Hrabě de Angelis, Glauco P Tocchini-Valentini, Tania Sorg, Yann Herault, Helen Parkinson, Ann-Marie Mallon, and Steve D M Brown

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Cardiac regeneration: epicardial mediated repair., Teresa Kennedy-Lydon and Nadia Rosenthal

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Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help., Juhyun Kim, Su Jeong Ryu, Keunhee Oh, Ji-Min Ju, Ji Yeong Jeon, Giri Nam, Dong-Sup Lee, Hang-Rae Kim, Joo Young Kim, Jun Chang, Thomas J. Sproule, Kyungho Choi, Derry C. Roopenian, and Eun Young Choi

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Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration., Jayendra Kumar Krishnaswamy, Arpita Singh, Uthaman Gowthaman, Renee Wu, Pavane Gorrepati, Manuela Sales Nascimento, Antonia Gallman, Dong Liu, Anne Marie Rhebergen, Samuele Calabro, Lan Xu, Patricia Ranney, Anuj Srivastava, Matthew Ranson, James D Gorham, Zachary McCaw, Steven R Kleeberger, Leonhard X Heinz, André C Müller, Keiryn L Bennett, Giulio Superti-Furga, Jorge Henao-Mejia, Fayyaz S Sutterwala, Adam Williams, Richard A Flavell, and Stephanie C Eisenbarth

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Nomenclature of Toso, Fas Apoptosis Inhibitory Molecule 3, and IgM FcR., Hiromi Kubagawa, Michael C Carroll, Chaim O Jacob, Karl S Lang, Kyeong-Hee Lee, Tak Mak, Monica McAndrews, Herbert C Morse, Garry P Nolan, Hiroshi Ohno, Günther H Richter, Ruth Seal, Ji-Yang Wang, Adrian Wiestner, and John E Coligan

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Glucocorticoid receptor and nuclear factor kappa-b affect three-dimensional chromatin organization., Tatyana Kuznetsova, Shuang-Yin Wang, Nagesha A Rao, Amit Mandoli, Joost H A Martens, Nils Rother, Aafke Aartse, Laszlo Groh, Eva M Janssen-Megens, Guoliang Li, Yijun Ruan, Colin Logie, and Hendrik G Stunnenberg

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Automated Update, Revision, and Quality Control of the Maize Genome Annotations Using MAKER-P Improves the B73 RefGen_v3 Gene Models and Identifies New Genes., MeiYee Law, Kevin L Childs, Michael S Campbell, Joshua C Stein, Andrew J Olson, Carson Holt, Nicholas Panchy, Jikai Lei, Dian Jiao, Carson M Andorf, Carolyn J Lawrence, Doreen Ware, Shin-Han Shiu, Yanni Sun, Ning Jiang, and Mark Yandell

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Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes., Chih-Ying Lee, Henning F Horn, Colin L Stewart, Brian Burke, Ewelina Bolcun-Filas, John C Schimenti, Michael E Dresser, and Roberto J Pezza

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PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal., Hsiang-Ying Lee, Xiaofei Gao, M Inmaculada Barrasa, Hu Li, Russell R Elmes, Luanne L. Peters, and Harvey F Lodish

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Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci., Elizabeth J Leslie, Margaret A Taub, Huan Liu, Karyn Meltz Steinberg, Daniel C Koboldt, Qunyuan Zhang, Jenna C Carlson, Jacqueline B Hetmanski, Hang Wang, David E Larson, Robert S Fulton, Youssef A Kousa, Walid D Fakhouri, Ali Naji, Ingo Ruczinski, Ferdouse Begum, Margaret M Parker, Tamara Busch, Jennifer Standley, Jennifer Rigdon, Jacqueline T Hecht, Alan F Scott, George L Wehby, Kaare Christensen, Andrew E Czeizel, Frederic W-B Deleyiannis, Brian C Schutte, Richard K Wilson, Robert A Cornell, Andrew C Lidral, George M. Weinstock, Terri H Beaty, Mary L Marazita, and Jeffrey C Murray

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Quantifying and optimizing single-molecule switching nanoscopy at high speeds., Yu Lin, Jane J Long, Fang Huang, Whitney C Duim, Stefanie Kirschbaum, Yongdeng Zhang, Lena K Schroeder, Aleksander A Rebane, Mary Grace M Velasco, Alejandro Virrueta, Daniel W Moonan, Junyi Jiao, Sandy Y Hernandez, Yongli Zhang, and Joerg Bewersdorf

The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ABCC6 gene., Qiaoli Li, John P. Sundberg, Michael A Levine, Sharon F Terry, and Jouni Uitto

Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors., Shaoyong Li, Chen Ling, Li Zhong, Mengxin Li, Qin Su, Ran He, Qiushi Tang, Dale L Greiner, Leonard D. Shultz, Michael A Brehm, Terence R Flotte, Christian Mueller, Arun Srivastava, and Guangping Gao

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Mutations in the Microtubule-Associated Protein 1A (Map1a) Gene Cause Purkinje Cell Degeneration., Ye Liu, Jeong Woong Lee, and Susan L. Ackerman

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Global genetic analysis in mice unveils central role for cilia in congenital heart disease., You Li, Nikolai T Klena, George C Gabriel, Xiaoqin Liu, Andrew J Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chienfu Chang, Hisato Yagi, Jovenal T San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, C Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia Smith, Janan T. Eppig, Laura G Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K Ganapathiraju, Kimimasa Tobita, Gregory J Pazour, and Cecilia W Lo

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Precision medicine: Look to the mice., K C Kent Lloyd, Terry Meehan, Arthur Beaudet, Stephen A Murray, Karen L. Svenson, Colin McKerlie, David West, Iva Morse, Helen Parkinson, Steve Brown, Ann-Marie Mallon, and Mark Moore

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Reproducibility: use mouse biobanks or lose them., Kent Lloyd, Craig Franklin, Cathleen Lutz, and Terry Magnuson

Prevalence and penetrance of ZFPM2 mutations and deletions causing congenital diaphragmatic hernia., M Longoni, M K Russell, F A High, K Darvishi, F I Maalouf, A Kashani, A A Tracy, C M Coletti, M Loscertales, K Lage, K G Ackerman, S A Woods, C Ward-Melver, D Andrews, Charles Lee, B R Pober, and P K Donahoe

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Cross-organism analysis using InterMine., Rachel Lyne, Julie Sullivan, Daniela Butano, Sergio Contrino, Joshua Heimbach, Fengyuan Hu, Alex Kalderimis, Mike Lyne, Richard N Smith, Radek Štěpán, Rama Balakrishnan, Gail Binkley, Todd Harris, Kalpana Karra, Sierra A T Moxon, Steven Neuhauser, Leyla Ruzicka, Mike Cherry, Joel E Richardson, Lincoln Stein, Monte Westerfield, Elizabeth Worthey, and Gos Micklem

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A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia., Dennis M Maddox, Gayle B. Collin, Akihiro Ikeda, C Herbert Pratt, Sakae Ikeda, Britt A Johnson, Ronald E. Hurd, Lindsay S Shopland, Juergen K. Naggert, Bo Chang, Mark P. Krebs, and Patsy M. Nishina

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High-throughput phenotyping and genetic linkage of cortical bone microstructure in the mouse., Kevin S Mader, Leah Rae Donahue, Ralph Müller, and Marco Stampanoni

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Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations., Ankit Malhotra, Yong Wang, Jill Waters, Ken Chen, Funda Meric-Bernstam, Ira M Hall, and Nicholas E Navin

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Degeneration and plasticity of the optic pathway in alström syndrome., R Manara, V Citton, P Maffei, Jan D. Marshall, Juergen K. Naggert, G Milan, R Vettor, A Baglione, A Vitale, C Briani, F Di Salle, and A Favaro

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Histone reader BRWD1 targets and restricts recombination to the Igk locus., Malay Mandal, Keith M Hamel, Mark Maienschein-Cline, Azusa Tanaka, Grace Teng, Jigyasa H Tuteja, Jeffrey J Bunker, Neil Bahroos, John J. Eppig, David G Schatz, and Marcus R Clark

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Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice., Mao Mao, Richard Smith, Marcel V Alavi, Jeffrey K Marchant, Mihai Cosma, Richard T Libby, Simon W M John, and Douglas B Gould

Alström Syndrome: Mutation Spectrum of ALMS1., Jan D. Marshall, Jean Muller, Gayle B. Collin, Gabriella Milan, Stephen F Kingsmore, Darrell Dinwiddie, Emily G Farrow, Neil A Miller, Francesca Favaretto, Pietro Maffei, Hélène Dollfus, Roberto Vettor, and Juergen K. Naggert

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Nonvenous origin of dermal lymphatic vasculature., Ines Martinez-Corral, Maria H Ulvmar, Lukas Stanczuk, Florence Tatin, Krishnakumar Kizhatil, Simon W M John, Kari Alitalo, Sagrario Ortega, and Taija Makinen

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Carcinogenic HPV infection in the cervical squamo-columnar junction., Jelena Mirkovic, Brooke E Howitt, Patrick Roncarati, Stephanie Demoulin, Meggy Suarez-Carmona, Pascale Hubert, Frank D. McKeon, Wa Xian, Anita Li, Philippe Delvenne, Christopher P Crum, and Michael Herfs

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Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells., Tapan Kumar Mistri, Arun George Devasia, Lee Thean Chu, Wei Ping Ng, Florian Halbritter, Douglas Colby, Ben Martynoga, Simon R Tomlinson, Ian Chambers, Paul Robson, and Thorsten Wohland

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MouseMine: a new data warehouse for MGI., Howie Motenko, Steven B. Neuhauser, M O'Keefe, and Joel E Richardson

Histopathology of the Human Inner Ear in Alström's Syndrome., Joseph B Nadol, Jan D. Marshall, and Roderick T Bronson

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Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice., Muhammad K K Niazi, Nimit Dhulekar, Diane Schmidt, Samuel Major, Rachel Cooper, Claudia Abeijon, Daniel Mario Gatti, Igor Kramnik, Bulent Yener, Metin Gurcan, and Gillian Beamer

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Systems approaches in integrative cardiac biology: Illustrations from cardiac heterocellular signalling studies., Hieu T Nim, Sarah E Boyd, and Nadia A Rosenthal

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CARFMAP: a curated pathway map fo cardiac fibroblasts., Hieu T. Nim, Milena B. Furtado, Mauro W. Costa, Nadia A. Rosenthal, and Sarah E. Boyd

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VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery., Hieu T Nim, Milena B Furtado, Mauro W Costa, Nadia A. Rosenthal, Hiroaki Kitano, and Sarah E Boyd

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Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment., Yael R Nobel, Laura M Cox, Francis F Kirigin, Nicholas A Bokulich, Shingo Yamanishi, Isabel Teitler, Jennifer Chung, Jiho Sohn, Cecily M Barber, David S Goldfarb, Kartik Raju, Sahar Abubucker, Yanjiao Zhou, Victoria E Ruiz, Huilin Li, Makedonka Mitreva, Alexander V Alekseyenko, George M. Weinstock, Erica Sodergren Weinstock, and Martin J Blaser

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A roadmap for the genetic analysis of renal aging., Gerda A Noordmans, Jan-Luuk Hillebrands, Harry van Goor, and Ron Korstanje

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C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD., Jacqueline G O'Rourke, Laurent P. Bogdanik, A K M G Muhammad, Tania F Gendron, Kevin J Kim, Andrew Austin, Janet Cady, Elaine Y Liu, Jonah Zarrow, Sharday Grant, Ritchie Ho, Shaughn Bell, Sharon Carmona, Megan Simpkinson, Deepti Lall, Kathryn Wu, Lillian Daughrity, Dennis W Dickson, Matthew B Harms, Leonard Petrucelli, Edward B Lee, Cathleen M. Lutz, and Robert H Baloh

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The phenotypic and molecular genetic spectrum of Alström syndrome in 44 Turkish kindreds and a literature review of Alström syndrome in Turkey., Ayşegül Ozantürk, Jan D. Marshall, Gayle B. Collin, Selma Düzenli, Robert P Marshall, Şükrü Candan, Tülay Tos, İhsan Esen, Mustafa Taşkesen, Atilla Çayır, Şükrü Öztürk, İhsan Üstün, Esra Ataman, Emin Karaca, Taha Reşid Özdemir, İlknur Erol, Fehime Kara Eroğlu, Deniz Torun, Erhan Parıltay, Elif Yılmaz-Güleç, Ender Karaca, M Emre Atabek, Nursel Elçioğlu, İlhan Satman, Claes Möller, Jean Muller, Juergen K. Naggert, and Rıza Köksal Özgül

KCNN Genes that Encode Small-Conductance Ca(2+)-Activated K(+) Channels Influence Alcohol and Drug Addiction., Audrey E Padula, William C Griffin, Marcelo F Lopez, Sudarat Nimitvilai, Reginald Cannady, Natalie S McGuier, Elissa J. Chesler, Michael F Miles, Robert W Williams, Patrick K Randall, John J Woodward, Howard C Becker, and Patrick J Mulholland

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Duration of Diabetes Predicts Aortic Pulse Wave Velocity and Vascular Events in Alström Syndrome., Richard B Paisey, Jamie Smith, Catherine Carey, Timothy Barrett, Fiona Campbell, Pietro Maffei, Jan D. Marshall, Christopher Paisey, Richard P Steeds, Nicola C Edwards, Susan Bunce, and Tarekegn Geberhiwot

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Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy., Chong-Xian Pan, Hongyong Zhang, Clifford G Tepper, Tzu-Yin Lin, Ryan R Davis, James G. Keck, Paramita M Ghosh, Parkash Gill, Susan Airhart, Carol J. Bult, David R Gandara, Edison Liu, and Ralph W de Vere White

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Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer., Hansoo Park, Sung-Yup Cho, Hyerim Kim, Deukchae Na, Jee Yun Han, Jeesoo Chae, Changho Park, Ok-Kyoung Park, Seoyeon Min, Jinjoo Kang, Boram Choi, Jimin Min, Jee Young Kwon, Yun-Suhk Suh, Seong-Ho Kong, Hyuk-Joon Lee, Edison T. Liu, Jong-Il Kim, Sunghoon Kim, Han-Kwang Yang, and Charles Lee

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Whole-genome characterization of chemoresistant ovarian cancer., Ann-Marie Patch, Elizabeth L Christie, Dariush Etemadmoghadam, Dale W Garsed, Joshy George, Sian Fereday, Katia Nones, Prue Cowin, Kathryn Alsop, Peter J Bailey, Karin S Kassahn, Felicity Newell, Michael C J Quinn, Stephen Kazakoff, Kelly Quek, Charlotte Wilhelm-Benartzi, Ed Curry, Huei San Leong, Anne Hamilton, Linda Mileshkin, George Au-Yeung, Catherine Kennedy, Jillian Hung, Yoke-Eng Chiew, Paul Harnett, Michael Friedlander, Michael Quinn, Jan Pyman, Stephen Cordner, Patricia O'Brien, Jodie Leditschke, Greg Young, Kate Strachan, Paul Waring, Walid Azar, Chris Mitchell, Nadia Traficante, Joy Hendley, Heather Thorne, Mark Shackleton, David K Miller, Gisela Mir Arnau, Richard W Tothill, Timothy P Holloway, Timothy Semple, Ivon Harliwong, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Senel Idrisoglu, Timothy J C Bruxner, Angelika N Christ, Barsha Poudel, Oliver Holmes, Matthew Anderson, Conrad Leonard, Andrew Lonie, Nathan Hall, Scott Wood, Darrin F Taylor, Qinying Xu, J Lynn Fink, Nick Waddell, Ronny Drapkin, Euan Stronach, Hani Gabra, Robert Brown, Andrea Jewell, Shivashankar H Nagaraj, Emma Markham, Peter J Wilson, Jason Ellul, Orla McNally, Maria A Doyle, Ravikiran Vedururu, Collin Stewart, Ernst Lengyel, John V Pearson, Nicola Waddell, Anna deFazio, Sean M Grimmond, and David D L Bowtell

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Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability., Shrivatsav Pattabiraman, Claudia Baumann, Daniela Guisado, John J. Eppig, John C Schimenti, and Rabindranath De La Fuente

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The transcriptional landscape of age in human peripheral blood., Marjolein J Peters, Roby Joehanes, Luke C Pilling, Claudia Schurmann, Karen N Conneely, Joseph Powell, Eva Reinmaa, George L. Sutphin, Alexandra Zhernakova, Katharina Schramm, Yana A Wilson, Sayuko Kobes, Taru Tukiainen, Yolande F Ramos, Harald H H Göring, Myriam Fornage, Yongmei Liu, Sina A Gharib, Barbara E Stranger, Philip L De Jager, Abraham Aviv, Daniel Levy, Joanne M Murabito, Peter J Munson, Tianxiao Huan, Albert Hofman, André G Uitterlinden, Fernando Rivadeneira, Jeroen van Rooij, Lisette Stolk, Linda Broer, Michael M P J Verbiest, Mila Jhamai, Pascal Arp, Andres Metspalu, Liina Tserel, Lili Milani, Nilesh J Samani, Pärt Peterson, Silva Kasela, Veryan Codd, Annette Peters, Cavin K Ward-Caviness, Christian Herder, Melanie Waldenberger, Michael Roden, Paula Singmann, Sonja Zeilinger, Thomas Illig, Georg Homuth, Hans-Jörgen Grabe, Henry Völzke, Leif Steil, Thomas Kocher, Anna Murray, David Melzer, Hanieh Yaghootkar, Stefania Bandinelli, Eric K Moses, Jack W Kent, Joanne E Curran, Matthew P Johnson, Sarah Williams-Blangero, Harm-Jan Westra, Allan F McRae, Jennifer A Smith, Sharon L R Kardia, Iiris Hovatta, Markus Perola, Samuli Ripatti, Veikko Salomaa, Anjali K Henders, Nicholas G Martin, Alicia K Smith, Divya Mehta, Elisabeth B Binder, K Maria Nylocks, Elizabeth M Kennedy, Torsten Klengel, Jingzhong Ding, Astrid M Suchy-Dicey, Daniel A Enquobahrie, Jennifer Brody, Jerome I Rotter, Yii-Der I Chen, Jeanine Houwing-Duistermaat, Margreet Kloppenburg, P Eline Slagboom, Quinta Helmer, Wouter den Hollander, Shannon Bean, Towfique Raj, Noman Bakhshi, Qiao Ping Wang, Lisa J Oyston, Bruce M Psaty, Russell P Tracy, Grant W Montgomery, Stephen T Turner, John Blangero, Ingrid Meulenbelt, Kerry J Ressler, Jian Yang, Lude Franke, Johannes Kettunen, Peter M Visscher, G Gregory Neely, Ron Korstanje, Robert L Hanson, Holger Prokisch, Luigi Ferrucci, Tonu Esko, Alexander Teumer, Joyce B J van Meurs, and Andrew D Johnson

Parallel Epidemics of Community-Associated Methicillin-Resistant Staphylococcus aureus USA300 Infection in North and South America., Paul J Planet, Lorena Diaz, Sergios-Orestis Kolokotronis, Apurva Narechania, Jinnethe Reyes, Galen Xing, Sandra Rincon, Hannah Smith, Diana Panesso, Chanelle Ryan, Dylan P Smith, Manuel Guzman, Jeannete Zurita, Robert Sebra, Gintaras Deikus, Rathel L Nolan, Fred C Tenover, George M. Weinstock, D Ashley Robinson, and Cesar A Arias

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Dysregulated expression of sterol O-acyltransferase 1 (Soat1) in the hair shaft of Hoxc13 null mice., Christopher S Potter, Michael J Kern, Mary Ann Baybo, Nathanael D Pruett, Alan R Godwin, John P. Sundberg, and Alexander Awgulewitsch

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Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice., Simon D Pouwels, Irene H Heijink, Uilke Brouwer, Renee Gras, Lisette E den Boef, H Marike Boezen, Ron Korstanje, Antoon J M van Oosterhout, and Martijn C Nawijn

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Dsp(rul): A spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome., C Herbert Pratt, Christopher S. Potter, Heather Fairfield, Laura G. Reinholdt, David E. Bergstrom, Belinda S. Harris, Ian Greenstein, Soheil S Dadras, Bruce T Liang, Paul N Schofield, and John P. Sundberg

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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice., Maximiliano Presa, Yi-Guang Chen, Alexandra E Grier, Edward H. Leiter, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, and David V. Serreze

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Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease., Wenning Qin, Stephanie L. Dion, Peter M. Kutny, Yingfan Zhang, Albert Cheng, Nathaniel L. Jillette, Ankit Malhotra, Aron M Geurts, Yi-Guang Chen, and Haoyi Wang

Loss of tumor suppressive microRNA-31 enhances TRADD/NF-κB signaling in glioblastoma., Rajani Rajbhandari, Braden C McFarland, Ashish Patel, Magda Gerigk, G Kenneth Gray, Samuel C Fehling, Markus Bredel, Nicolas F Berbari, Hyunsoo Kim, Margaret P Marks, Gordon P Meares, Tanvi Sinha, Jeffrey Chuang, Etty N Benveniste, and Susan E Nozell

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Genetic Background is a Key Determinant of Glomerular Extracellular Matrix Composition and Organization., Michael J Randles, Adrian S Woolf, Jennifer L Huang, Adam Byron, Jonathan D Humphries, Karen L Price, Maria Kolatsi-Joannou, Sophie Collinson, Thomas Denny, David Knight, Aleksandr Mironov, Toby Starborg, Ron Korstanje, Martin J Humphries, David A Long, and Rachel Lennon

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High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping., Christoph D Rau, Brian Parks, Yibin Wang, Eleazar Eskin, Petr Simecek, Gary A. Churchill, and Aldons J Lusis

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Elimination of HIV-1-Infected Primary T Cell Reservoirs in an In Vitro Model of Latency., Stephen A Rawlings, Francis Alonzo, Lina Kozhaya, Victor J Torres, and Derya Unutmaz

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The Role of Platelet-Activating Factor in Mesangial Pathophysiology., Anna Reznichenko and Ron Korstanje

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Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival., Dennis S Rice, Jorgelina M Calandria, William C Gordon, Bokkyoo Jun, Yongdong Zhou, Claire M Gelfman, Songhua Li, Minghao Jin, Eric J Knott, Bo Chang, Alex Abuin, Tawfik Issa, David Potter, Kenneth A Platt, and Nicolas G Bazan

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SWDreader: A wavelet-based algorithm using spectral phase to characterize spike-wave morphological variation in genetic models of absence epilepsy., C D Richard, A Tanenbaum, B Audit, A Arneodo, Andre Khalil, and Wayne N. Frankel

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Visual annotation display (VLAD): a tool for finding functional themes in lists of genes., Joel E Richardson and Carol J. Bult

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Discriminatory Indices of Typing Methods for Epidemiologic Analysis of Contemporary Staphylococcus aureus Strains., Marcela Rodriguez, Patrick G Hogan, Sarah W Satola, Emily Crispell, Todd Wylie, Hongyu Gao, Erica Sodergren, George M. Weinstock, Carey-Ann D Burnham, and Stephanie A Fritz

Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs., Derry C. Roopenian, Benjamin E. Low, Gregory J. Christianson, Gabriele Proetzel, Thomas J Sproule, and Michael V. Wiles

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The transcriptional profile of coronary arteritis in Kawasaki disease., Anne H Rowley, Kristine M Wylie, Kwang-Youn A Kim, Adam J Pink, Amy Yang, Rebecca Reindel, Susan C Baker, Stanford T Shulman, Jan M Orenstein, Mark W Lingen, George M. Weinstock, and Todd N Wylie

Hematopoietic androgen receptor deficiency promotes visceral fat deposition in male mice without impairing glucose homeostasis., K B Rubinow, S Wang, L J den Hartigh, S Subramanian, G J Morton, F W Buaas, D Lamont, N Gray, Robert E. Braun, and S T Page

Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1., Nicolas Ruffin, Vedran Brezar, Diana Ayinde, Cécile Lefebvre, Julian Schulze Zur Wiesch, Jan van Lunzen, Maximilian Bockhorn, Olivier Schwartz, Hakim Hocini, Jean-Daniel Lelievre, Jacques Banchereau, Yves Levy, and Nabila Seddiki

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Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population., Holly Rutledge, Jeanette Baran-Gale, Fernando Pardo-Manuel de Villena, Elissa J. Chesler, Gary A. Churchill, Praveen Sethupathy, and Samir N P Kelada

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Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo., Felix Scheuplein, Deanna J Lamont, Matthew E Poynter, Jonathan E Boyson, David V. Serreze, Lennart K A Lundblad, Robert Mashal, and Robert Schaub

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Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection., Xaver Sewald, Mark S Ladinsky, Pradeep D Uchil, Jagadish Beloor, Ruoxi Pi, Christin Herrmann, Nasim Motamedi, Thomas T Murooka, Michael A Brehm, Dale L Greiner, Leonard D. Shultz, Thorsten R Mempel, Pamela J Bjorkman, Priti Kumar, and Walther Mothes

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Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis., Baochen Shi, Michaela Chang, John Martin, Makedonka Mitreva, Renate Lux, Perry Klokkevold, Erica Sodergren Weinstock, George M. Weinstock, Susan K Haake, and Huiying Li

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Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice., Petr Simecek, Gary Churchill, Hyuna Yang, Lucy B. Rowe, Lieselotte Herberg, David V. Serreze, and Edward H. Leiter

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A mouse geneticist's practical guide to CRISPR applications., Priti Singh, John C Schimenti, and Ewelina Bolcun-Filas

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The BioMart community portal: an innovative alternative to large, centralized data repositories., Damian Smedley, Syed Haider, Steffen Durinck, Luca Pandini, Paolo Provero, James Allen, Olivier Arnaiz, Mohammad Hamza Awedh, Richard Baldock, Giulia Barbiera, Philippe Bardou, Tim Beck, Andrew Blake, Merideth Bonierbale, Anthony J Brookes, Gabriele Bucci, Iwan Buetti, Sarah Burge, Cédric Cabau, Joseph W Carlson, Claude Chelala, Charalambos Chrysostomou, Davide Cittaro, Olivier Collin, Raul Cordova, Rosalind J Cutts, Erik Dassi, Alex Di Genova, Anis Djari, Anthony Esposito, Heather Estrella, Eduardo Eyras, Julio Fernandez-Banet, Simon Forbes, Robert C Free, Takatomo Fujisawa, Emanuela Gadaleta, Jose M Garcia-Manteiga, David Goodstein, Kristian Gray, José Afonso Guerra-Assunção, Bernard Haggarty, Dong-Jin Han, Byung Woo Han, Todd Harris, Jayson Harshbarger, Robert K Hastings, Richard D Hayes, Claire Hoede, Shen Hu, Zhi-Liang Hu, Lucie Hutchins, Zhengyan Kan, Hideya Kawaji, Aminah Keliet, Arnaud Kerhornou, Sunghoon Kim, Rhoda Kinsella, Christophe Klopp, Lei Kong, Daniel Lawson, Dejan Lazarevic, Ji-Hyun Lee, Thomas Letellier, Chuan-Yun Li, Pietro Lio, Chu-Jun Liu, Jie Luo, Alejandro Maass, Jerome Mariette, Thomas Maurel, Stefania Merella, Azza Mostafa Mohamed, Francois Moreews, Ibounyamine Nabihoudine, Nelson Ndegwa, Céline Noirot, Cristian Perez-Llamas, Michael Primig, Alessandro Quattrone, Hadi Quesneville, Davide Rambaldi, James Reecy, Michela Riba, Steven Rosanoff, Amna Ali Saddiq, Elisa Salas, Olivier Sallou, Rebecca Shepherd, Reinhard Simon, Linda Sperling, William Spooner, Daniel M Staines, Delphine Steinbach, Kevin Stone, Elia Stupka, Jon W Teague, Abu Z Dayem Ullah, Jun Wang, Doreen Ware, Marie Wong-Erasmus, Ken Youens-Clark, Amonida Zadissa, Shi-Jian Zhang, and Arek Kasprzyk

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GXD: a community resource of mouse Gene Expression Data., Constance M. Smith, Jacqueline H. Finger, Terry F. Hayamizu, Ingeborg J. McCright, Jingxia Xu, Janan T. Eppig, James A. Kadin, Joel E Richardson, and Martin Ringwald

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Expanding the mammalian phenotype ontology to support automated exchange of high throughput mouse phenotyping data generated by large-scale mouse knockout screens., Cynthia Smith and Janan T. Eppig

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Minor genomic differences between related B6 and B10 mice affect severity of schistosome infection by governing the mode of dendritic cell activation., Patrick M Smith, Thomas J. Sproule, Vivek M. Philip, Derry C. Roopenian, and Miguel J Stadecker

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Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression., Elizabeth Snyder, Ramani Soundararajan, Manju Sharma, Andrea Dearth, Benjamin Smith, and Robert E Braun

Small bowel resection induces long-term changes in the enteric microbiota of mice., J Sommovilla, Y Zhou, R C Sun, P M Choi, J Diaz-Miron, N Shaikh, Erica Sodergren Weinstock, B B Warner, George M. Weinstock, P I Tarr, and B W Warner

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APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction., Ileana Soto, Leah C. Graham, Hannah J Richter, Stephen N Simeone, Jake E Radell, Weronika Grabowska, W Keith Funkhouser, Megan C Howell, and Gareth R. Howell

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RASA3 is a critical inhibitor of RAP1-dependent platelet activation., Lucia Stefanini, David S Paul, Ray F. Robledo, E Ricky Chan, Todd M Getz, Robert A Campbell, Daniel O Kechele, Caterina Casari, Raymond Piatt, Kathleen M Caron, Nigel Mackman, Andrew S Weyrich, Matthew C Parrott, Yacine Boulaftali, Mark D Adams, Luanne L. Peters, and Wolfgang Bergmeier

Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function., Michael L. Stitzel, Ina Kycia, Romy Kursawe, and Duygu Ucar

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An integrated map of structural variation in 2,504 human genomes., Peter H Sudmant, Tobias Rausch, Eugene J Gardner, Robert E Handsaker, Alexej Abyzov, John Huddleston, Yan Zhang, Kai Ye, Goo Jun, Markus Hsi-Yang Fritz, Miriam K Konkel, Ankit Malhotra, Adrian M Stütz, Xinghua Shi, Francesco Paolo Casale, Jieming Chen, Fereydoun Hormozdiari, Gargi Dayama, Ken Chen, Maika Malig, Mark J P Chaisson, Klaudia Walter, Sascha Meiers, Seva Kashin, Erik Garrison, Adam Auton, Hugo Y K Lam, Xinmeng Jasmine Mu, Can Alkan, Danny Antaki, Taejeong Bae, Eliza Cerveira, Peter Chines, Zechen Chong, Laura Clarke, Elif Dal, Li Ding, Sarah Emery, Xian Fan, Madhusudan Gujral, Fatma Kahveci, Jeffrey M Kidd, Yu Kong, Eric-Wubbo Lameijer, Shane McCarthy, Paul Flicek, Richard A Gibbs, Gabor Marth, Christopher E Mason, Androniki Menelaou, Donna M Muzny, Bradley J Nelson, Amina Noor, Nicholas F Parrish, Matthew Pendleton, Andrew Quitadamo, Benjamin Raeder, Eric E Schadt, Mallory Romanovitch, Andreas Schlattl, Robert Sebra, Andrey A Shabalin, Andreas Untergasser, Jerilyn A Walker, Min Wang, Fuli Yu, Chengsheng Zhang, Jing Zhang, Xiangqun Zheng-Bradley, Wanding Zhou, Thomas Zichner, Jonathan Sebat, Mark A Batzer, Steven A McCarroll, Ryan E Mills, Mark B Gerstein, Ali Bashir, Oliver Stegle, Scott E Devine, Charles Lee, Evan E Eichler, and Jan O Korbel

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Excavating the Genome: Large-Scale Mutagenesis Screening for the Discovery of New Mouse Models., John P Sundberg, Soheil S Dadras, Kathleen A Silva, Victoria E. Kennedy, Stephen A. Murray, James M Denegre, Paul N Schofield, Lloyd E King, Michael V. Wiles, and C Herbert Pratt

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Animal Models for Alopecia Areata: What and Where?, John P Sundberg, Kevin McElwee, Michael A Brehm, Lishan Su, and Lloyd E King

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Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis., Fengyun Sun, Yasuhiro Fujiwara, Laura G. Reinholdt, Jianjun Hu, Ruth L. Saxl, Christopher L. Baker, Petko M. Petkov, Kenneth Paigen, and Mary Ann Handel

Dietary vitamin A regulates wingless-related MMTV integration site signaling to alter the hair cycle., Liye Suo, John P. Sundberg, and Helen B Everts

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Scaling up phenotyping studies., Karen L. Svenson

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription., Zhonghui Tang, Oscar Junhong Luo, Xingwang Li, Meizhen Zheng, Jacqueline Jufen Zhu, Przemyslaw Szalaj, Pawel Trzaskoma, Adriana Magalska, Jakub Wlodarczyk, Blazej Ruszczycki, Paul Michalski, Emaly Piecuch, Ping Wang, Danjuan Wang, Simon Zhongyuan Tian, May Penrad-Mobayed, Laurent M Sachs, Xiaoan Ruan, Chia-Lin Wei, Edison T. Liu, Grzegorz M Wilczynski, Dariusz Plewczynski, Guoliang Li, and Yijun Ruan

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MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1., Zijian Tang, Siyuan Dai, Yishu He, Rosalinda A. Doty, Leonard D. Shultz, Stephen B. Sampson, and Chengkai Dai

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One small step for muscle: a new micropeptide regulates performance., Joanne Tonkin and Nadia Rosenthal

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Immunotherapy: The path to win the war on cancer?, Suzanne L Topalian, Jedd D Wolchok, Timothy A Chan, Ira Mellman, Karolina Palucka, Jacques Banchereau, Steven A Rosenberg, and K Dane Wittrup

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Inhibition of Bromodomain Proteins for the Treatment of Human Diffuse Large B-cell Lymphoma., Sally E Trabucco, Rachel M Gerstein, Andrew M Evens, James E Bradner, Leonard D. Shultz, Dale L Greiner, and Hong Zhang

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A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells., S-W Tsaih, Maximiliano Presa, S Khaja, A E Ciecko, David V. Serreze, and Y-G Chen

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Visual impairment in an optineurin mouse model of primary open-angle glaucoma., Henry C Tseng, Thorfinn T Riday, Celia McKee, Catherine E Braine, Howard Bomze, Ian Barak, Carrie Marean-Reardon, Simon W M John, Benjamin D Philpot, and Michael D Ehlers

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CD73 Is Associated with Poor Prognosis in High-Grade Serous Ovarian Cancer., Martin Turcotte, Kathleen Spring, Sandra Pommey, Guillaume Chouinard, Isabelle Cousineau, Joshy George, Gregory M Chen, Deena M A Gendoo, Benjamin Haibe-Kains, Thomas Karn, Kurosh Rahimi, Cécile Le Page, Diane Provencher, Anne-Marie Mes-Masson, and John Stagg

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Cell-specific gene promoters are marked by broader spans of H3K4me3 and are associated with robust gene expression patterns., Duygu Ucar and Dashzeveg Bayarsaihan

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Amplification of the bromodomain-containing protein 4 gene in ovarian high-grade serous carcinoma is associated with worse prognosis and survival., Duygu Ucar and Douglas I Lin

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Pathophysiology of T follicular helper cells in humans and mice., Hideki Ueno, Jacques Banchereau, and Carola G Vinuesa

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Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells., Martin Vaeth, Isabelle Zee, Axel R Concepcion, Mate Maus, Patrick Shaw, Cynthia Portal-Celhay, Aleena Zahra, Lina Kozhaya, Carl Weidinger, Jennifer Philips, Derya Unutmaz, and Stefan Feske

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Super-enhancers delineate disease-associated regulatory nodes in T cells., Golnaz Vahedi, Yuka Kanno, Yasuko Furumoto, Kan Jiang, Stephen C J Parker, Michael R Erdos, Sean R Davis, Rahul Roychoudhuri, Nicholas P Restifo, Massimo Gadina, Zhonghui Tang, Yijun Ruan, Francis S Collins, Vittorio Sartorelli, and John J O'Shea

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Inhibition of HIV infection by caerin 1 antimicrobial peptides., Scott VanCompernolle, Patricia B Smith, John H Bowie, Michael J Tyler, Derya Unutmaz, and Louise A Rollins-Smith