Title

Analysis of morphine responses in mice reveals a QTL on Chromosome 7.

Document Type

Article

Publication Date

9-2-2016

JAX Source

F1000Res 2016 Sep 2; 5:2156

PMID

27746909

Abstract

In this study we identified a quantitative trait locus (QTL) on mouse Chromosome 7 associated with locomotor activity and rearing post morphine treatment. This QTL was revealed after correcting for the effects of another QTL peak on Chromosome 10 using composite interval mapping. The positional candidate genes are Syt9 and Ppfibp2. Several other genes within the interval are linked to neural processes, locomotor activity, and the defensive response to harmful stimuli. F1000Res 2016 Sep 2; 5:2156