Title

A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.

Document Type

Article

Publication Date

2016

JAX Source

Adv Exp Med Biol 2016; 854:177-83.

PMID

26427409

Abstract

Mouse models provide important resources for many areas of vision research, pertaining to retinal development, retinal function and retinal disease. The Translational Vision Research Models (TVRM) program uses chemical mutagenesis to generate new mouse models for vision research. In this chapter, we report the identification of mouse models for Grm1, Grk1 and Lrit3. Each of these is characterized by a primary defect in the electroretinogram. All are available without restriction to the research community. Adv Exp Med Biol 2016; 854:177-83.

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