Title

Human embryo research and the 14-day rule.

Document Type

Article

Publication Date

6-1-2017

JAX Source

Development 2017 Jun 1; 144(11):1923-1925

PMID

28559237

Abstract

In many jurisdictions, restrictions prohibit the culture of human embryos beyond 14 days of development. However, recent reports describing the successful maintenance of embryos in vitro to this stage have prompted many in the field to question whether the rule is still appropriate. This Spotlight article looks at the original rationale behind the 14-day rule and its relevance today in light of advances in human embryo culture and in the derivation of embryonic-like structures from human pluripotent stem cells.

Development 2017 Jun 1; 144(11):1923-1925.