Title

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea.

Document Type

Article

Publication Date

8-8-2017

Keywords

Genome, Archaeal, Genome, Bacterial, Genomics, Metagenomics, Sequence Analysis, DNA

JAX Source

Nat Biotechnol 2017 Aug; 35(8):725-731.

PMID

28787424

DOI

https://doi.org/10.1038/nbt.3893

Abstract

We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity. Nat Biotechnol 2017 Aug; 35(8):725-731.