Title

Cardiac regeneration: All work and no repair?

Document Type

Article

Publication Date

3-29-2017

JAX Source

Sci Transl Med 2017 Mar 29; 9(383):eaad9019

PMID

28356512

Abstract

Structural changes in the developing heart may influence the limited regenerative capacity of the adult heart. We examine how the workload exerted on the adult mammalian heart may limit regenerative capability and discuss recent therapies that demonstrate beneficial effects through unloading the heart.

Sci Transl Med 2017 Mar 29; 9(383):eaad9019.