Gene affecting superoxide dismutase activity linked to the histocompatibility complex in H-2 congenic mice.
Animals, Biological Evolution, Genes, Genes, Regulator, Genetic Linkage, H-2 Antigens, Liver, Major Histocompatibility Complex, Mice, Superoxide Dismutase
Science 1980 Jan 4; 207(4426):86-7.
The activity of cyanide-sensitive, Cu-Zn superoxide dismutase (SOD) was studied in liver sytosols from H-2 congenic strains of mice. Higher SOD activity was found in livers of mice having H-2b/A.BY, B10, and C3H.SW/haplotypes than in those of H-2a, H-2k and H-2d haplotypes. Segregation studies supported these correlations. In H-2 recombinant strains of mice, the genes influencing the liver SOD activity occur, as ascertained by mapping techniques, at or near the H-2d region of the major histocompatibility complex.
Novak, R; Bosze, Z; Matkovics, B; and Fachet, J, "Gene affecting superoxide dismutase activity linked to the histocompatibility complex in H-2 congenic mice." (1980). Subject Strain Bibliography 1980. 736.