Faculty Research 1970 - 1979

Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy.

B Ballou
G Levine
T R. Hakala
D Solter


Murine teratocarcinomas were located in mice by external gamma-ray scintigraphy with an iodine-125-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by an iodine-125-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.