Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis.
Animal, Genes, Leukemia-Experimental: et, fg, Male, Mice, Mice-Nude: mi, Mouse-Leukemia-Viruses: ip, SUPPORT-U-S-GOVT-P-H-S
J-Natl-Cancer-Inst. 1976 May; 56(5):1073-4.
Leukemia-prone hairless (HRS/J; hr/hr) mice had significantly higher leukemia virus titers than did the leukemia-resistant nonmutants (hr/ + and +/+). This difference was ascribed to the allelic substitution at a single gene locus; at 6 months of age it averaged 13-fold, immediately preceding the large divergence in leukemia incidence between the mutant and nonmutant mice.
Heiniger, H J.; Huebner, R J.; and Meier, H, " Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis." (1976). Faculty Research 1970 - 1979. 654.
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