Faculty Research 1970 - 1979
Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis.
Document Type
Article
Publication Date
1976
Keywords
Animal, Genes, Leukemia-Experimental: et, fg, Male, Mice, Mice-Nude: mi, Mouse-Leukemia-Viruses: ip, SUPPORT-U-S-GOVT-P-H-S
First Page
1073
Last Page
1074
JAX Source
J-Natl-Cancer-Inst. 1976 May; 56(5):1073-4.
Abstract
Leukemia-prone hairless (HRS/J; hr/hr) mice had significantly higher leukemia virus titers than did the leukemia-resistant nonmutants (hr/ + and +/+). This difference was ascribed to the allelic substitution at a single gene locus; at 6 months of age it averaged 13-fold, immediately preceding the large divergence in leukemia incidence between the mutant and nonmutant mice.
Recommended Citation
Heiniger HJ,
Huebner RJ,
Meier H.
Effect of allelic substitutions at the hairless locus on endogenous ecotropic murine leukemia virus titers and leukemogenesis. J-Natl-Cancer-Inst. 1976 May; 56(5):1073-4.