Faculty Research 1970 - 1979

Development of Dickie's small eye, a mutation in the house mouse.

Document Type

Article

Publication Date

1978

Keywords

Animal, Cataract: fg, Coloboma: fg, Heterozygote, Homozygote, Mice, Mice-Mutant-Strains, Retina: ab, SUPPORT-U-S-GOVT-P-H-S

First Page

81

Last Page

86

JAX Source

Anat-Embryol-(Berl). 1978 Dec 5; 155(1):81-6.

Abstract

A new semidominant mutation in the laboratory mouse, Dickie's small eye (Dey), is described. It is localized on chromosome 2. Heterozygotes show reduced body size, small eyes with coloboma, small or lacking lens with cataract, abnormal folding of the retina and reduction of the pigment layer. The anterior chamber is usually missing. Homozygotes apparently die early in

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