Faculty Research 1980 - 1989

Title

Macrophage content and immunogenicity of C57BL/6J and BALB/cByJ methylcholanthrene-induced sarcomas.

Document Type

Article

Publication Date

1980

Keywords

Cell-Count, Female, Macrophages: im, Methylcholanthrene, Mice, Mice-Inbred-BALB-C, Mice-Inbred-C57BL, Sarcoma-Experimental: ci, im, pa, SUPPORT-U-S-GOVT-P-H-S, Transplantation-Immunology

JAX Location

44,246

JAX Source

Int-J-Cancer. 1980 Dec 15; 26(6):831-5.

Grant

CA20920

Abstract

A total of 33 methylcholanthrene-induced sarcomas, growing in C57BL/6J or BALB/cByJ mice, were tested for their immunogenicity and for their relative macrophage content. No relationship was demonstrated between these two characteristics. These results suggest that the direct correlation between macrophage content and immunogenicity demonstrated in rat tumor model systems may not hold for other systems.

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