Faculty Research 1980 - 1989

Title

An amplified endogenous retroviral sequence on the murine Y chromosome related to murine leukemia viruses and viruslike 30S sequences.

Document Type

Article

Publication Date

1989

Keywords

Base-Sequence, DNA-Viral: an, Gene-Amplification, Male, Mice, Mice-Inbred-C57BL, Molecular-Sequence-Data, Mouse-Leukemia-Viruses: ge, Repetitive-Sequences-Nucleic-Acid, SUPPORT-NON-U-S-GOVT, SUPPORT-U-S-GOVT-P-H-S, Y-Chromosome

Grant

GM20919

Abstract

A highly repeated sequence on the murine Y chromosome was cloned and characterized. The DNA sequence of the viral long terminal repeats (LTRs) showed that the 5' and 3' LTRs were approximately 90% homologous. The LTRs are generally unrelated to any previously reported viral LTR but are somewhat similar to the viruslike 30S sequences.

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