Faculty Research 1980 - 1989

Title

Sensitive model with which to detect athermal effects of non-ionizing electromagnetic radiation.

Document Type

Article

Publication Date

1989

Keywords

Beta-Galactosidases: me, re, Electromagnetic-Fields, Electromagnetics, Escherichia-Coli: en, ge, re, Galactosidases: re, Models-Biological, Plasmids: re, SUPPORT-U-S-GOVT-NON-P-H-S, Transfection

JAX Location

1830

Abstract

To clarify the potential of non-ionizing electromagnetic radiation to cause biological effects by athermal mechanisms, and to initiate elucidation of those mechanisms, a model system amenable to scrutiny at the molecular level has been designed and characterized. Assessment of beta-galactosidase activity in E. coli JM101 containing the plasmid pUC8 provides a sensitive assay with many important advantages. The ability to examine at the molecular level each of the processes involved in producing beta-galactosidase should permit elucidation of the molecular mechanism(s) that give rises to an observed effect.

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