Faculty Research 1980 - 1989

Title

Linkage and recombination of VH gene markers, Np and Nb, in recombinant inbred strains of mice.

Document Type

Article

Publication Date

1981

Keywords

Animal, Binding-Sites-Antibody, Crossing-Over-(Genetics), Heterozygote, Homozygote, Immunoglobulin-Idiotypes, Immunoglobulin-Variable-Region, Linkage-(Genetics), Mice, Mice-Inbred-C57BL, Mice-Inbred-DBA, Mice-Inbred-Strains, Recombination-Genetic, SUPPORT-U-S-GOVT-P-H-S

JAX Source

Immunol-Lett. 1981 Aug; 3(3):169-72.

Grant

NO1CP33255

Abstract

Mice of 24 recombinant inbred (RI) strains of the BXD series were typed for Igh markers, Np and Nb. In 22 strains these markers were concordant with the allotype (10 DBA/2-like and 12 C57BL/6-like). Strains BXD-20 and BXD-27 had a recombinant haplotype; their allotype was DBA/2-like but the Np and Nb characteristics were C57B/6-like.

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