Faculty Research 1980 - 1989
[Genetic study of paradoxical sleep in mice. Connection with coloration genes]
Document Type
Article
Publication Date
1980
Keywords
Chromosome-Mapping, English-Abstract, Genes-Dominant, Hybridization, Male, Mice, Mice-Inbred-Strains, Sleep-REM: ph
First Page
175
Last Page
183
JAX Source
Waking-Sleeping. 1980 Apr-Jun; 4(2):175-83.
Abstract
The study of Paradoxical Sleep (PS) from 94 male mice belonging to five inbred strains: C57BR/cdOrl (BR), BALB/cOrl (C), AKROrl, A/JOrl (A/J) and C57BL/6-c2J (B6-c2J), reciprocal F1 hybrids between BR and C strains and backcrosses between F1 hybrids and BR or C was carried out. The results showed that 1) night PS duration was independent from that of day PS; 2) C type of PS seemed to be dominant over BR type; 3) C type is linked to the albino gene; and 4) the albino gene, per se, is not involved in PS regulation. From these results a two locus model was elaborated. This model explains most of the results. The nature of such a genetic support was discussed.
Recommended Citation
Valatx JL,
Cespuglio R,
Paut L,
Bailey DW.
[Genetic study of paradoxical sleep in mice. Connection with coloration genes] Waking-Sleeping. 1980 Apr-Jun; 4(2):175-83.