Hemolytic anemia in the mouse. Report of a new mutation and clarification of its genetics.
Anemia-Hemolytic-Congenital: bl, fg, Animal, Comparative-Study, Genes-Recessive, Mice, Mice-Inbred-Strains, Mutation, Rodent-Diseases: fg, Spectrin: ge, SUPPORT-NON-U-S-GOVT, SUPPORT-U-S-GOVT-NON-P-H-S, SUPPORT-U-S-GOVT-P-H-S
J-Hered. 1983 Mar-Apr; 74(2):88-92.
AM25305, HD00254, AM21836
A new mutation causing spherocytic, hemolytic anemia has been discovered in the house mouse. It is inherited as a single autosomal recessive gene, allelic with both sph and ha, which, in turn, were shown to be allelic with each other. A revised nomenclature for the three apparent alleles is proposed: sph (formerly sph), sphha (formerly ha), and sph2Bc (the new mutation). Like the other murine hemolytic anemias, sph2Bc involves a defect in the red blood cell membrane protein, spectrin.
Unger, A E.; Harris, M J.; Bernstein, S E.; Falcone, J C.; and Lux, S E., " Hemolytic anemia in the mouse. Report of a new mutation and clarification of its genetics." (1983). Faculty Research 1980 - 1989. 441.
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