Faculty Research 1980 - 1989
A serum protein polymorphism determinant on chromosome 9 of Mus musculus.
Document Type
Article
Publication Date
1980
Keywords
Blood-Protein-Electrophoresis, Blood-Proteins: ge, Chromosome-Mapping, Crosses-Genetic, Female, Genes-Structural, Malate-Dehydrogenase: ge, Male, Mannosephosphate-Isomerase: ge, Mice, Mice-Inbred-Strains: ge, Polymorphism-(Genetics), Recombination-Genetic, SUPPORT-U-S-GOVT-P-H-S, Transferrin: ge
First Page
571
Last Page
576
JAX Location
43,665
JAX Source
MGG. 1980; 177(4):571-6.
Abstract
Genetic polymorphism for a previously undescribed serum protein has been found among inbred strains of Mus musculus. The new serum protein locus, gene symbol Sep-1, has been located on Chromosome 9, gene order Lap-1--Sep-1--Mpi-1--d--Mod-1, by utilizing information obtained from 52 recombinant inbred strains together with standard genetic backcrosses. The strain distribution pattern for this locus, supernatant malic enzyme, and transferrin also on Chromosome 9, are given for 67 inbred strains. Because the genotype of SEP-1 can be determined for individual mice without killing them, Sep-1 is a very useful gene in linkage studies and experimental biology.
Recommended Citation
Eicher EM,
Taylor BA,
Leighton SC,
Womack JE.
A serum protein polymorphism determinant on chromosome 9 of Mus musculus. MGG. 1980; 177(4):571-6.