Adrenal changes in genetically hypothyroid mice.
Animal, Female, Hypothyroidism: pp, pa, Mice, Mice-Mutant-Strains, SUPPORT-NON-U-S-GOVT, SUPPORT-U-S-GOVT-P-H-S, Thyroid-Gland-Desiccated
J-Endocrinol. 1984 Sep; 102(3):277-80.
The adrenocortical X-zone was very poorly developed in young female mice homozygous for the hypothyroid, hyt, mutation, Feeding the mice thyroid powder resulted in the development of an X-zone. This subsequently degenerated in the same way as the X-zone found in the normal litter-mates of the mutants. We suggest that the adrenocortical effects may be due to changes in prolactin stimulation consequent upon the lack of response to thyrotrophin of the mutants.
Shire, J G. and Beamer, W G., " Adrenal changes in genetically hypothyroid mice." (1984). Faculty Research 1980 - 1989. 532.