Faculty Research 1980 - 1989

Title

Mapping of the X-linked immune deficiency mutation (xid) of CBA/N mice.

Document Type

Article

Publication Date

1980

Keywords

Chromosome-Mapping, Crosses-Genetic, Female, Gene-Frequency, Immunologic-Deficiency-Syndromes: fg, Male, Mice, Mice-Inbred-CBA: ge, Mutation, Recombination-Genetic, X-Chromosome: im

JAX Location

43,843

JAX Source

J-Immunol. 1980 Apr; 124(4):1875-7.

Abstract

CBA/N mice carry a recessive mutation at the X-linked immune deficiency (xid) locus that precludes their response to certain thymus-independent (TI) antigens. We have determined that xid is situated on the X-chromosome between the genes Ta (tabby) and Hyp (hypophosphatemia), genetic distances being Ta-6.6 +/- 1.8-xid-12.2 +/- 2.3-Hyp.

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