Faculty Research 1980 - 1989
Chromosomal location of a major tRNA gene cluster of Xenopus laevis.
Document Type
Article
Publication Date
1984
Keywords
Chromosome-Mapping, DNA-Ribosomal: ge, Female, Nucleic-Acid-Hybridization, Oocytes: an, Organ-Specificity, Repetitive-Sequences-Nucleic-Acid, RNA-Transfer: ge, SUPPORT-NON-U-S-GOVT, SUPPORT-U-S-GOVT-P-H-S, Xenopus-laevis: ge
First Page
254
Last Page
260
JAX Source
Chromosoma 1984;90(4):254-60
Grant
GM23241
Abstract
In Xenopus laevis, genes encoding tRNAPhe, tRNATyr, tRNAMet1, tRNAAsn, tRNAAla, tRNALeu, and tRNALys are clustered within a 3.18-kb (kilobase) fragment of DNA. This fragment is tandemly repeated some 150 times in the haploid genome and its components are found outside the repeat only to a limited extent. The fragment hybridizes in situ to a single site very near the telomere on the long arm of one of the acrocentric chromosomes of the group comprising chromosomes 13-18. All the chromosomes of this group also hybridize with DNA coding for oocyte-specific 5S RNA. The tRNA gene cluster is slightly proximal to the cluster of 5S RNA genes.
Recommended Citation
Fostel J,
Narayanswami S,
Hamkalo B,
Clarkson SG,
Pardue ML.
Chromosomal location of a major tRNA gene cluster of Xenopus laevis. Chromosoma 1984;90(4):254-60